Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
82 Results for "
PCa
" in MedChemExpress (MCE) Product Catalog:
Products (82)
82 Results for "PCa" in MCE Product Catalog:
24
17
MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 μM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 μM and unstresses RPMI 8226 cells with an IC50 of 0.14 μM . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth .
4
Research Areas:
Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K + channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research .
2
2 Cited Publications
Synonyms: PSMA I&T; PNT-2002
PSMA I&T is an effective inhibitor of prostate-specific membrane antigen (PSMA). PSMA I&T can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) .
2
2 Cited Publications
Cat. No.: HY-N7043
CAS No.: 142796-21-2
1
1
1 Cited Publications
Cat. No.: HY-P99274
CAS No.: 1417158-65-6
Synonyms: BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody
1
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCa; Chromozym PCa diacetate
Target:
Research Areas:
1
Target:
1
1
1 Cited Publications
Cat. No.: HY-N12127
CAS No.: 899430-01-4
Category:
Target:
1
1 Cited Publications
Cat. No.: HY-P700709
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: E-NPP 1; NPPase; ENPP1; NPPS; PC1; PDNP1; Ly-41 Antigen; M6S1; M6S1NPP1; NPP1; PCa1; PCa1ARHR2
Cat. No.: HY-156751A
CAS No.: 2753651-10-2
Synonyms: RO7656594
Target:
Research Areas:
GDC-2992 (Compound 28A) is an orally bioavailable androgen receptor (AR) PROTAC degrader. GDC-2992 degrads AR with a DC50 value of 2.7 nM and inhibits proliferation with an IC50 valude of 9.7 nM in VCaPcells. GDC-2992 can be used for prostatic cancer study .
Cat. No.: HY-W1048558A
Synonyms: mPEG2000-COOH
Cat. No.: HY-P10816
CAS No.: 1426656-94-1
Synonyms: Ac-(DLeu)LLLRVK-Amba
Cat. No.: HY-162412
CAS No.: 2841308-96-9
Target:
Research Areas:
PROTAC AR/AR-V7 degrader-1 (27c) is a PROTAC-based and dual AR, AR-V7 degrader, with DC50 values of 2.67 and 2.64 μM for AR and AR-V7, respectively. PROTAC AR/AR-V7 degrader-1 (27c) induces apoptosis (Red: AR antagonist; Blue: E3 ligase ligand; Black: linker) .
Category:
Infection other families Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
