100-83-4
100-83-4
Chemical Structure
3-Hydroxybenzaldehyde
Synonym(s): M-Hydroxybenzaldehyde
- CAS No.: 100-83-4
- Formula:C7H6O2
- Molecular Weight:122.12
IUPAC Name: 3-hydroxybenzaldehyde
InChIKey: IAVREABSGIHHMO-UHFFFAOYSA-N
SMILES: O=CC1=CC=CC(O)=C1
Biological Activity: 3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295). 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis[1][2][3][4].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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3-Hydroxybenzaldehyde | 99.89% | 3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295). 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis. | ||||||||||||||||||||
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3-Hydroxybenzaldehyde (Standard) | ≥98% | 3-Hydroxybenzaldehyde (Standard) is the analytical standard of 3-Hydroxybenzaldehyde. This product is intended for research and analytical applications. 3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295). 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis. | ||||||||||||||||||||
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m-Tolualdehyde | 99.58% | m-Tolualdehyde (3-Methylbenzaldehyde) is an aldehyde metabolite produced by m-xylene metabolism, and it bidirectionally regulates the CYP 2B1, CYP 2E1, and CYP 4B1 isoenzymes in the respiratory tract of rats. m-Tolualdehyde serves as an oxidation substrate and carbon source for Pseudomonas Pxy, and it can be oxidized to m-toluic acid in an NAD+ -dependent manner. m-Tolualdehyde exerts a dose-dependent inhibitory effect on CYP 2B1 and CYP 2E1 in the nasal mucosa and lungs of rats, and a dose-dependent activating effect on pulmonary CYP 4B1. m-Tolualdehyde can form aldehyde-heme adducts with the heme group of cytochrome P450. m-Tolualdehyde can be used in studies related to metabolic enzymes in the respiratory tract of rats. | ||||||||||||||||||||
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Protocatechualdehyde | 99.87% | Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent. | ||||||||||||||||||||
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2,5-Dihydroxybenzaldehyde (Standard) | ≥98% | 2,5-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,5-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L. | ||||||||||||||||||||
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m-Anisaldehyde (Standard) | ≥98% | m-Anisaldehyde (Standard) (3-Methoxybenzaldehyde (Standard)) is the analytical standard of m-Anisaldehyde (HY-W007346). This product is intended for research and analytical applications. m-Anisaldehyde (3-Methoxybenzaldehyde) is an aromatic aldehyde that exhibits low fumigant insecticidal activity against Lycoriella ingenua larvae. m-Anisaldehyde is a characteristic serum metabolite that is negatively correlated with uric acid in late pregnancy and negatively correlated with thyroid autoantibodies TPOAb and TgAb. m-Anisaldehyde can be used in studies of thyroid autoimmunity. | ||||||||||||||||||||
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2,4-Dihydroxybenzaldehyde | 99.90% | 2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions. | ||||||||||||||||||||
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P-Hydroxybenzaldehyde-13C6 | P-Hydroxybenzaldehyde-13C6 is the 13C-labeled p-Hydroxybenzaldehyde (HY-Y0313). p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. | |||||||||||||||||||||
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p-Hydroxybenzaldehyde (Standard) | 99.95% | p-Hydroxybenzaldehyde (Standard) is the analytical standard of p-Hydroxybenzaldehyde. This product is intended for research and analytical applications. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. | ||||||||||||||||||||
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p-Hydroxybenzaldehyde-13C | p-Hydroxybenzaldehyde-13C is the 13C-labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations. | |||||||||||||||||||||
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3-Chlorobenzaldehyde | 98.71% | 3-Chlorobenzaldehyde (m-Chlorobenzenecarboxaldehyde) is a substrate of rat liver microsomal aldehyde dehydrogenase (mALDH) and undergoes mALDH-mediated dehydrogenation to generate the corresponding carboxylic acid. 3-Chlorobenzaldehyde is a chlorine-substituted aromatic benzaldehyde organic synthesis building block and can serve as an intermediate for research related to organic synthesis. | ||||||||||||||||||||
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References
- [1]. Kong BS, et al. Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.PLoS One. 2016 Mar 22;11(3):e0149394. [Content Brief]
- [2]. Paixão JA, et al. 3-Hydroxybenzaldehyde. Acta Crystallogr C. 2000 Nov;56 Pt 11:1348-50. [Content Brief]
- [3]. Chen K Y, et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. International Journal of Antimicrobial Agents, 2023, 62(5): 106963. [Content Brief]
- [4]. Muthu S, et al. Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation[J]. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:789-99. [Content Brief]
