1 Result for "

PF-4942847

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PF-4942847" in MCE Product Catalog:

Cat. No.: HY-108336
CAS No.: 1046859-34-0
Research Areas:  

Cancer

PF-4942847 is an orally active HSP90 inhibitor with an IC50 of approximately 50 nM. PF-4942847 induces apoptosis in osteosarcoma cells, increases the proportion of cells in the sub-G1 phase and PARP cleavage, reduces the expression of Akt, Erk, MYC, c-MET and STAT-3, and regulates HSP expression. PF-4942847 can be used in studies related to osteosarcoma and HSP90 .
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