2 Results for "

PI3K/Akt/mTOR-IN-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PI3K/Akt/mTOR-IN-7" in MCE Product Catalog:

Cat. No.: HY-183272
CAS No.: 2925588-01-6
PI3K/Akt/mTOR-IN-7 is an AKT/mTOR and JAK2/STAT3 inhibitor. PI3K/Akt/mTOR-IN-7 restores p-Akt, p-mTOR, and p-STAT3 expression, reduces pro-apoptotic Caspase-3 mRNA expression. PI3K/Akt/mTOR-IN-7 reduces intracellular ROS accumulation and inhibits NO production. PI3K/Akt/mTOR-IN-7 can be used for research on stroke, Alzheimer's disease and Parkinson's disease .
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Cat. No.: HY-147614
CAS No.: 2456295-65-9
Target:  

PI3K mTOR

Research Areas:  

Cancer

PI3K/mTOR Inhibitor-7 (Compound 19i) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-7 shows 4.7-fold higher potency than the positive control gedatolisib (0.3 vs. 1.4 μM, IC50 values). PI3K/mTOR Inhibitor-7 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-7 has the potential for the research of cancer diseases .
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