1 Result for "

PI3Kα-IN-30

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PI3Kα-IN-30" in MCE Product Catalog:

Cat. No.: HY-182368
Target:  

PI3K Akt Apoptosis

Research Areas:  

Cancer

PI3Kα-IN-30 is an orally active, selective PI3Kα inhibitor with an IC50 of 2.8 nM. PI3Kα-IN-30 inhibits cancer cell proliferation, as well as the phosphorylation of Akt (S473) and pS6 (S240/244). PI3Kα-IN-30 shows low growth inhibitory activity against normal somatic cell lines at a concentration of 30 μM. PI3Kα-IN-30 induces cancer cell apoptosis and exerts anti-tumor efficacy in xenograft models. PI3Kα-IN-30 can be used for the research of breast cancer .
loading...
    loading...