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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
PKG1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "PKG1" in MCE Product Catalog:
Cat. No.: HY-155106
Target:
Research Areas:
SMA4 is a selective PKG1α activator with basal EC50 value of 29 μM. SMA4 facilitates phosphorylation of the known PKG1 substrate, vasodilator-stimulated phosphoprotein (VASP), and inhibits human pulmonary arterial smooth muscle cells (hPASMC) proliferation. SMA4 can be used for cardiovascular disease research [1].
Cat. No.: HY-RS11154
Target:
Research Areas:
PRKG1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRKG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-151203
CAS No.: 2773367-58-9
Target:
Research Areas:
PKG1α activator 3 is a PKG1α activator (EC50 basal/partial=13/0.52 μM). PKG1α activator 3 shows anti-proliferative effects to smooth muscle cell, and can be used in cardiovascular disease research [1].
Cat. No.: HY-P702647
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PRKG1; CGKI; Prev. PRKGR1B; Protein Kinase, CGMP-Dependent, Regulatory, Type I, Beta; Prev. PRKG1B; CGMP-Dependent Protein Kinase I; PKG1; CGMP-Dependent Protein Kinase; PKG; CGKI-Alpha; Protein Kinase, CGMP-Dependent, Type I; CGKI-BETA; CGMP-Dependent Pr
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-180585
Research Areas:
LOXL2/sGC modulator-2 (Compound 9k) is a selective and orally active lysyl oxidase-like 2 (LOXL2) and soluble guanylate cyclase (sGC) dual-target regulator. LOXL2/sGC modulator-2 shows inhibitory activity for LOXL2 with an IC50 of 0.1 μM and can activate sGC. LOXL2/sGC modulator-2 can ameliorate vascular remodeling and reduce pulmonary artery pressure. LOXL2/sGC modulator-2 can downregulate PKG1, PCNA, α-SMA, collagen I and fibronectin levels. LOXL2/sGC modulator-2 can be used for the research of pulmonary arterial hypertension [1].
Cat. No.: HY-P71234
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRKG1; CGKI; Prev. PRKGR1B; Protein Kinase, CGMP-Dependent, Regulatory, Type I, Beta; Prev. PRKG1B; CGMP-Dependent Protein Kinase I; PKG1; CGMP-Dependent Protein Kinase; PKG; CGKI-Alpha; Protein Kinase, CGMP-Dependent, Type I; CGKI-BETA; CGMP-Dependent Pr
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
