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PNAs

" in MedChemExpress (MCE) Product Catalog:

153

Inhibitors & Agonists

10

Fluorescent Dyes

9

Biochemical Assay Reagents

138

Peptides

3

Natural
Products

3

Recombinant Proteins

15

Antibodies

3

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119244

    Dipeptidyl Peptidase Metabolic Disease
    Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .
    Gly-Pro-pNA hydrochloride
  • HY-123275B
    H-D-Phe-Pip-Arg-pNA acetate
    1 Publications Verification

    S-2238 acetate

    Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
    H-D-Phe-Pip-Arg-pNA acetate
  • HY-123275A
    H-D-Phe-Pip-Arg-pNA hydrochloride
    1 Publications Verification

    S-2238 hydrochloride

    Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
    H-D-Phe-Pip-Arg-pNA hydrochloride
  • HY-131409

    D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride

    Fluorescent Dye Others
    D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .
    D-Val-Leu-Lys-pNA dihydrochloride
  • HY-P4202

    Suc-AEPF-pNA

    Biochemical Assay Reagents Others
    Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays .
    Suc-Ala-Glu-Pro-Phe-pNA
  • HY-W008129

    Drug Intermediate Bacterial Infection
    H-D-cis-Hyp-OH is a proline derivative and also a substrate of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. H-D-cis-Hyp-OH serves as a starting material for the synthesis of conformationally constrained pyrrolidine PNA adenine monomers .
    H-D-cis-Hyp-OH
  • HY-P4476
    Suc-AAPA-pNA
    1 Publications Verification

    Ser/Thr Protease Others
    Suc-AAPA-pNA is a substrate for chymotrypsin A and elastase. Suc-AAPA-pNA can be used for enzyme activity assay .
    Suc-AAPA-pNA
  • HY-P4581

    Suc-ALPF-pNA

    FKBP Others
    Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA) is a synthetic polypeptide substrate that targets FK506-binding protein (FKBP). Suc-Ala-Leu-Pro-Phe-pNA can be used to determine peptidyl-prolyl cis-trans isomerase activity via the chymotrypsin-coupled assay. Suc-Ala-Leu-Pro-Phe-pNA serves as a substrate for human FK506-binding protein hFKBP-12 in the chymotrypsin-FKBP coupled PPIase assay. Suc-Ala-Leu-Pro-Phe-pNA is applicable for the detection and research of PPIase activity .
    Suc-Ala-Leu-Pro-Phe-pNA
  • HY-114150D

    Kallikrein Others
    D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
    D-Val-Leu-Arg-pNA acetate
  • HY-NP0182

    PNA (Biotinylated)

    Fluorescent Dye Others
    Peanut Agglutinin (PNA) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Biotinylated is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (Biotinylated)
  • HY-P10094

    Fluorescent Dye Others
    β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
    β-Ala-Gly-Arg-pNA
  • HY-P4460

    Ser/Thr Protease Cancer
    AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
    AAA-pNA
  • HY-P4518

    Ser/Thr Protease Others
    Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
    Z-Val-Gly-Arg-pNA
  • HY-P4453

    Caspase Cancer
    Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
    Boc-Ala-Ala-Asp-pNA
  • HY-122142A

    S-2366 hydrochloride

    APC Factor XI Biochemical Assay Reagents Others
    Pyr-Pro-Arg-pNA (S2366) hydrochloride is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA hydrochloride can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA hydrochloride can be used for measurement of APC amidolytic activity .
    Pyr-​Pro-​Arg-​pNA hydrochloride
  • HY-P2091

    Caspase Inflammation/Immunology
    Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
    Ac-YVAD-pNA
  • HY-P4515

    Cathepsin Others
    Z-Phe-Arg-pNA is a substrate of Cathepsin L .
    Z-Phe-Arg-pNA
  • HY-123275C

    S-2238 dihydrochloride

    Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
    H-D-Phe-Pip-Arg-pNA dihydrochloride
  • HY-134113

    CBZ-Chromozym TH

    Biochemical Assay Reagents Others
    Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity .
    Z-Gly-Pro-Arg-pNA
  • HY-P4582

    Suc-FAAF-pNA

    Ser/Thr Protease Others
    Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .
    Suc-Phe-Ala-Ala-Phe-pNA
  • HY-P4455

    Bacterial Infection
    Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
    Boc-AAG-pNA
  • HY-NP0138

    PNA (Fluorescein)

    Fluorescent Dye Others
    Peanut Agglutinin (PNA) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Fluorescein is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (Fluorescein)
  • HY-123275

    S-2238

    Fluorescent Dye Others
    H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
    H-D-Phe-Pip-Arg-pNA
  • HY-P5027

    Ser/Thr Protease Kallikrein Factor Xa Thrombin Cardiovascular Disease
    Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, plasmin, factor Xa and Kallikrein .
    Cbz-Lys-Arg-pNA
  • HY-P6027A

    Fluorescent Dye Others
    H-D-CHA-Ala-Arg-pNA diacetate is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-P6027). H-D-CHA-Ala-Arg-pNA diacetate is a chromogenic substrate for the amidolytic assay .
    H-D-CHA-Ala-Arg-pNA diacetate
  • HY-126809A

    Bz-PFR-pNA hydrochloride

    Factor Xa Others
    Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .
    Bz-Pro-Phe-Arg-pNA hydrochloride
  • HY-P4458

    Ser/Thr Protease Cancer
    Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
    Boc-QAR-pNA
  • HY-P4482

    Bacterial Infection
    Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
    Suc-AAPE-pNA
  • HY-P4470

    Ser/Thr Protease Cancer
    Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
    Phe-Pro-Ala-pNA
  • HY-P4464

    Ser/Thr Protease Cancer
    Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
    Ala-Phe-Pro-pNA
  • HY-P4658

    Dipeptidyl Peptidase Others
    H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .
    H-Val-Ala-pNA
  • HY-P4464A

    Ser/Thr Protease Cancer
    Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .
    Ala-Phe-Pro-pNA TFA
  • HY-W011701

    Amino Acid Derivatives Others
    H-Glu-pNA is a glutamic acid derivative .
    H-Glu-pNA
  • HY-NP0156

    PNA (Rhodamine)

    Fluorescent Dye Others
    Peanut Agglutinin (PNA) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) Rhodamine is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (Rhodamine)
  • HY-NP093

    PNA (CY3)

    Fluorescent Dye Others
    Peanut Agglutinin (PNA) CY3 is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut Agglutinin (PNA) CY3 is a biological material or organic compound that can be used in life science research .
    Peanut Agglutinin (CY3)
  • HY-137858

    Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride

    Fluorescent Dye Others
    H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
    H-Gly-Arg-pNA hydrochloride
  • HY-151738

    ADC Linker Others
    Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Fmoc-Aeg(N3)-OH
  • HY-P11392

    Cholinesterase (ChE) Biochemical Assay Reagents Others
    Ac-IEAR-pNA is the chromogenic substrate for quantifying endotoxin levels. Ac-IEAR-pNA is cleaved by HuBChE to produce p-nitroaniline product .
    Ac-IEAR-pNA
  • HY-122142

    S-2366

    APC Factor XI Biochemical Assay Reagents Others
    Pyr-Pro-Arg-pNA (S2366) is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA can be used for measurement of APC amidolytic activity .
    Pyr-​Pro-​Arg-​pNA
  • HY-W011155

    P-pNA TFA

    Amino Acid Derivatives Others
    L-Proline p-nitroanilide (P-pNA) TFA is aproline derivatives.
    L-Proline p-nitroanilide TFA
  • HY-P10448

    Boc-LGR-pNA acetate

    Fluorescent Dye Others
    Boc-Leu-Gly-Arg-pNA is a chromogenic synthetic substrate .
    Boc-Leu-Gly-Arg-pNA acetate
  • HY-P10001

    Z-Ile-Glu-Thr-Asp-pNA

    Caspase Cancer
    Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
    Z-IETD-pNA
  • HY-151778

    ADC Linker Others
    Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-Abg(N3)-OH
  • HY-108409

    Etienic acid; Testosterone-17β-carboxylic acid; 3-Oxoandrost-4-ene-17β-carboxylic acid

    Drug Derivative Metabolic Disease Cancer
    Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research .
    Progesterone carboxylic acid
  • HY-P5974

    Z-Tyr-Val-Ala-Asp-pNA

    Caspase Others
    Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
    Z-YVAD-pNA
  • HY-P10666

    Caspase Others
    Ac-VDQQD-pNA is a substrate of Caspase 2 and can be cleaved to produce yellow pNA (p-nitroaniline) .
    Ac-VDQQD-pNA
  • HY-126809

    Bz-PFR-pNA

    Kallikrein Ser/Thr Protease Parasite Factor Xa Others
    Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA can be used in Factor XII assay .
    Bz-Pro-Phe-Arg-pNA
  • HY-P10084

    Caspase Others
    Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
    Ac-VAD-pNA
  • HY-W713878

    Caspase Others
    Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
    Ac-VDVAD-pNA
  • HY-P4477

    Ser/Thr Protease Others
    Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity .
    Suc-AAPR-pNA

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