70967-97-4

Suc-AAPF-pNA Chemical Structure
70967-97-4

Chemical Structure

Suc-AAPF-pNA

Synonym(s): Suc-Ala-Ala-Pro-Phe-pNA

  • CAS No.: 70967-97-4
  • Formula:C30H36N6O9
  • Molecular Weight:624.64

InChIKey: YHUKYRGKNPQLRF-WJNSRDFLSA-N

SMILES: OC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@H](C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O

Biological Activity: Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-P2573 		Suc-AAPF-pNA 99.55% Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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