128802-76-6
128802-76-6
Chemical Structure
Suc-Ala-Glu-Pro-Phe-pNA
Synonym(s): Suc-AEPF-pNA
- CAS No.: 128802-76-6
- Formula:C32H38N6O11
- Molecular Weight:682.68
InChIKey: NXIHRDNJQWUSLK-KMAVCZJNSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(N[C@H](C(NC(C=C2)=CC=C2[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)[C@H](CCC(O)=O)NC([C@H](C)NC(CCC(O)=O)=O)=O
Biological Activity: Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Suc-Ala-Glu-Pro-Phe-pNA | 99.45% | Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays. | ||||||||||||||||||||
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References
- [1]. Hidaka M, et al. Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin1. Biochem Biophys Res Commun. 2018;499(3):681-687. [Content Brief]
- [2]. Duncan KE, et al. Discovery and characterization of a nonphosphorylated cyclic peptide inhibitor of the peptidylprolyl isomerase, Pin1. J Med Chem. 2011;54(11):3854-3865. [Content Brief]
- [3]. Kay DF, et al. Dissecting the functional behavior of the differentially phosphorylated prolyl isomerase, Pin1. Protein Sci. 2024;33(9):e5138. [Content Brief]
Keywords
