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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
PROTAC HDAC4 Degrader-2
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "PROTAC HDAC4 Degrader-2" in MCE Product Catalog:
Cat. No.: HY-184524
CAS No.: 3035189-46-6
PROTAC HDAC4 Degrader-2 is a class IIa selective negative control for HDAC4 PROTAC degraders, with an IC50 of 0.15 μM against HDAC4 and a cellular IC50 of 0.18 μM. PROTAC HDAC4 Degrader-2 fails to effectively recruit the VHL E3 ligase, and thus does not induce significant degradation of HDAC4 protein .
Cat. No.: HY-174444A
PROTAC HDAC degrader-2 TFA is a selective class IIb dual histone deacetylase (HDAC6 and HDAC10) PROTAC degrader, with DC50 values of 13 nM and 29 nM against HDAC6 and HDAC10, respectively. It does not degrade class I (HDAC1/8) and class IIa (HDAC4/7) histone deacetylases .
Cat. No.: HY-174444
PROTAC HDAC degrader-2 is a selective class IIb dual histone deacetylase (HDAC6 and HDAC10) PROTAC degrader, with DC50 values of 13 nM and 29 nM against HDAC6 and HDAC10, respectively. It does not degrade class I (HDAC1/8) and class IIa (HDAC4/7) histone deacetylases .
Cat. No.: HY-W039803
CAS No.: 340736-76-7
Research Areas:
HDAC4 ligand-2 is a HDAC4 ligand, which can be used for the synthesis of PROTACs, such as PROTAC HDAC4 Degrader-2 (HY-184524) .
Cat. No.: HY-184526
Target:
Research Areas:
HOOC-PEG5-N-(C3H7-isopropyl)-NH2 is a PROTAC linker that can be used for the synthesis of PROTACs, such as PROTAC HDAC4 Degrader-2 (HY-184524) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
