HDAC4 ligand-2
Based on 1 Customer Validation
HDAC4 ligand-2 is a HDAC4 ligand, which can be used for the synthesis of PROTACs, such as PROTAC HDAC4 Degrader-2 (HY-184524).
For research use only. We do not sell to patients.
- CAS No.: 340736-76-7
- Formula: C10H5F3N2O3
- Molecular Weight:258.15
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
|
HDAC4 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
82.25 μM
Compound: B10
|
Cytotoxicity against human MT2 cells after 4 days by XTT assay
Cytotoxicity against human MT2 cells after 4 days by XTT assay
|
[PMID: 19053778] |
| MT2 | EC50 |
3.06 μM
Compound: B10
|
Antiviral activity against HIV1 3B in human MT2 cells assessed as inhibition of p24 antigen level after 4 days by ELISA
Antiviral activity against HIV1 3B in human MT2 cells assessed as inhibition of p24 antigen level after 4 days by ELISA
|
[PMID: 19053778] |
Chemical Information
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CAS No. 340736-76-7
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Appearance Solid
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Molecular Weight 258.15
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Formula C10H5F3N2O3
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SMILES
O=C(C1=CC=C(C=C1)C2=NOC(C(F)(F)F)=N2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)