2 Results for "

Pyrrolidino-pyrimidine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Pyrrolidino-pyrimidine" in MCE Product Catalog:

Cat. No.: HY-150720
CAS No.: 2244061-66-1
Purity:  98.81%
Target:  

JAK IFNAR

Research Areas:  

Inflammation/Immunology

TYK2-IN-12 (compound 30) is an orally active, potent and selective TYK2 (tyrosine kinase 2) inhibitor, with a Ki of 0.51 nM. TYK2-IN-12 inhibits IL-12 induced IFNγ, with IC50 values of 2.7 and 7.0 μM in human and mouse whole blood, respectively. TYK2-IN-12 can be used for psoriasis research .
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Cat. No.: HY-P11927
Target:  

GSK-3

Research Areas:  

Cancer

BiS3 is a selective hyperbivalent macrocyclic peptide GSK3β inhibitor, with a Kd of 0.28 nM and an IC50 of 4.8 nM against GSK3β. BiS3 is applicable to studies related to GSK3β signaling and colorectal cancer .
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