1 Result for "

SH17

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SH17" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-187212
Target:  

STAT HDAC Apoptosis

Research Areas:  

Cancer

SH-17 is a STAT3 and HDAC inhibitor, with a Kd of 0.87 μM for STAT3, and IC50 values of 115.2 nM and 9.8 nM for HDAC1 and HDAC6, respectively. SH-17 blocks intracellular ATP production and mitochondrial oxidative phosphorylation, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. SH-17 is applicable to colon cancer research .
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