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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
SMARCA2B bromodomains
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SMARCA2B bromodomains" in MCE Product Catalog:
Cat. No.: HY-122645
CAS No.: 1915012-19-9
Target:
Research Areas:
SMARCA2-IN-4 (Compound 26) is an inhibitor for SWI/SNF chromatin remodeling complexe SMARCA by targeting the bromodomains. SMARCA2-IN-4 exhibits high affinity for PB1(5), SMARCA2B and SMARCA4 with Kd of 124, 262 and 417 nM .
Cat. No.: HY-151531
CAS No.: 2819989-60-9
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PBRM1-BD2-IN-4 is a PBRM1-BD2 inhibitor with an IC50 of 0.2 μM, and its Kd values for PBRM1-BD2 and PBRM1-BD5 are 5.5 μM and 11.1 μM, respectively. PBRM1-BD2-IN-4 selectively inhibits the proliferation of PBRM1-dependent prostate cancer cells. PBRM1-BD2-IN-4 can be used in studies related to prostate cancer .
Cat. No.: HY-133908
CAS No.: 1914047-60-1
Target:
Research Areas:
PFI-3 Control is an inactive analog of PFI-3 (HY-12409), serving as an inactive negative control. PFI-3 Control shows no detectable binding activity toward purified PB1 (5), SMARCA2A, SMARCA2B, and SMARCA4 family VIII bromodomain proteins .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
