SMARCA2-IN-4
SMARCA2-IN-4 (Compound 26) is an inhibitor for SWI/SNF chromatin remodeling complexe SMARCA by targeting the bromodomains. SMARCA2-IN-4 exhibits high affinity for PB1(5), SMARCA2B and SMARCA4 with Kd of 124, 262 and 417 nM.
For research use only. We do not sell to patients.
- CAS No.: 1915012-19-9
- Formula: C17H19ClN4O
- Molecular Weight:330.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All SWI/SNF Complex Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 1915012-19-9
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Molecular Weight 330.81
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Formula C17H19ClN4O
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SMILES
CN(CC1)CCN1/C=C2CCN(C\2=N3)C4=CC=CC(Cl)=C4C3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topics Chromatin Remodelling: A Key Target in Cardiovascular Disease Therapy And Beyond
Chromatin Remodelling: A Key Target in Cardiovascular Disease Therapy And BeyondChromatin remodelling refers to the dynamic regulation of nucleosome organization and chromatin accessibility by ATP-dependent chromatin-remodelling complexes, histone-modifying enzymes, and associated epigenetic regulators.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)