1915012-19-9
1915012-19-9
Chemical Structure
SMARCA2-IN-4
- CAS No.: 1915012-19-9
- Formula:C17H19ClN4O
- Molecular Weight:330.81
IUPAC Name: (E)-6-chloro-3-((4-methylpiperazin-1-yl)methylene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one
InChIKey: VLPRXFLUVHYBBT-VAWYXSNFSA-N
SMILES: CN(CC1)CCN1/C=C2CCN(C\2=N3)C4=CC=CC(Cl)=C4C3=O
Biological Activity: SMARCA2-IN-4 (Compound 26) is an inhibitor for SWI/SNF chromatin remodeling complexe SMARCA by targeting the bromodomains. SMARCA2-IN-4 exhibits high affinity for PB1(5), SMARCA2B and SMARCA4 with Kd of 124, 262 and 417 nM[1].
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SMARCA2-IN-4 | SMARCA2-IN-4 (Compound 26) is an inhibitor for SWI/SNF chromatin remodeling complexe SMARCA by targeting the bromodomains. SMARCA2-IN-4 exhibits high affinity for PB1(5), SMARCA2B and SMARCA4 with Kd of 124, 262 and 417 nM. | |||||||||||||||||||||
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References
Keywords
