2 Results for "

SUCNR1-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SUCNR1-IN-1" in MCE Product Catalog:

Cat. No.: HY-154946
CAS No.: 2711753-52-3
Purity:  99.39%
Target:  

Succinate Receptor 1

Research Areas:  

Inflammation/Immunology

SUCNR1-IN-1 is an orally active SUCNR1 inhibitor. SUCNR1-IN-1 exhibits inhibitory rates of 23% and 56% against rat and mouse SUCNR1 at 100 μM, respectively. SUCNR1-IN-1 can be used in the research of rheumatoid arthritis .
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Cat. No.: HY-183639
Research Areas:  

Cancer

SUCNR1 antagonist-1 is an orally active SUCNR1 antagonist. SUCNR1 antagonist-1 forms stable, water-bridged hydrogen bonds with key residue Glu22 1.31 to stabilize binding conformation and modulates protein conformational flexibility. SUCNR1 antagonist-1 blocks succinate-mediated SUCNR1 signaling and induces cell apoptosis. SUCNR1 antagonist-1 can be used for the research of colorectal carcinoma .
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