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Silybin B (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Silybin B (Standard)" in MCE Product Catalog:

Silybin B (Standard)
Silybin B (Standard)
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Cat. No.: HY-N7046R
CAS No.: 142797-34-0
Synonyms: Silibinin B (Standard)
Category:  

Flavanonols Glycine soya Flavonoids Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae

Target:  

Reference Standards JNK Amyloid-β p38 MAPK Apoptosis

Silybin (Silibinin B) (Standard) is the analytical standard of Silybin B (HY-N7046). This product is intended for research and analytical applications. Silybin B (Silibinin B) is an orally active amyloid-β aggregation inhibitor and ATR pathway activator, that can cross the blood-brain barrier. Silybin B inhibits Aβ fibril formation and promotes amorphous aggregate formation, while activating the ATR-mediated DNA damage repair pathway and inhibiting JNK/p38 MAPK signaling. Silybin B can reduce Cisplatin (HY-17394)-induced neuronal DNA damage and apoptosis. Silybin B has anti-oxidative stress, cell cycle regulation and neuroprotective activities. Silybin B is mainly used in the study of Alzheimer's disease and Cisplatin chemotherapy-related neurotoxicity .
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