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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Steroid 5
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Steroid 5" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: ONO-9302; SKF105657
Target:
Research Areas:
Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne .
Cat. No.: HY-N2489
CAS No.: 56786-63-1
Synonyms: BrassinoSteroid BB 16; DI 31
Target:
Research Areas:
5α-Hydroxy-laxogenin (Brassinosteroid BB 16; DI 31) is a derivative of laxogenin, a spirostane-type steroid. 5α-Hydroxy-laxogenin serves as a plant-derived anabolic agent and is used as a dietary supplement .
Synonyms: Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite
Target:
Research Areas:
D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.
Target:
Research Areas:
SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 µM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression .
Cat. No.: HY-123323
CAS No.: 134067-56-4
Target:
Research Areas:
MK-0434 is an orally active steroid 5α-reductase inhibitor. MK-0434 specifically inhibits steroid 5α-reductase, thereby reducing the level of dihydrotestosterone (DHT) in the body. MK-0434 can be used in the study of benign prostatic hyperplasia .
Cat. No.: HY-19144
CAS No.: 119347-91-0
Target:
Research Areas:
ONO-3805 is an early lead compound of a non-steroidal 5α-reductase inhibitor, used to inhibit the conversion of testosterone to dihydrotestosterone, with potential effects in inhibiting benign prostatic hyperplasia.
Cat. No.: HY-106363
CAS No.: 103497-68-3
Synonyms: L 654066
Target:
Research Areas:
MK-0963 is a steroidal 5α-reductase inhibitor. MK-0963 reduces serum dihydrotestosterone (DHT) concentrations in a dose-dependent manner. MK-0963 can be used for the study of dihydrotestosterone-related diseases such as benign prostate hyperplasia (BPH) .
Cat. No.: HY-106129
CAS No.: 176975-26-1
Synonyms: LY 320236
Target:
Research Areas:
Izonsteride (Compound LY320236) is an inhibitor of 5α-reductase (IC50 = 11.6 nM for type I; 7.37 nM for type II). LY320236 inhibits the activity of steroid 5α-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity .
Cat. No.: HY-133949
CAS No.: 82073-91-4
Target:
Research Areas:
8,11-Eicosadiynoic acid, an unsaturated fatty acid, is a steroid 5α-reductase inhibitor. 8,11-Eicosadiynoic acid can be used for the research of acne .
Cat. No.: HY-P705411
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRD5A1; SR Type 1; Steroid 5 Alpha-Reductase 1; S5AR 1; 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1; Steroid 5-Alpha-Reductase Type I; Steroid-5-Alpha-Reductase, Alpha Polypeptide 1 (3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 1); Steroid 5-Alpha-Reduct
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-107385R
CAS No.: 119169-78-7
Synonyms: ONO-9302 (Standard); SKF105657 (Standard)
Target:
Research Areas:
Epristeride (Standard) is the analytical standard of Epristeride. This product is intended for research and analytical applications. Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne .
Cat. No.: HY-175719
Target:
Research Areas:
SRD5A1-IN-2 is a inhibitor of steroid 5α-reductase type-1 (SRD5A1), with an IC50 of 8.5 μM. SRD5A1-IN-2 downregulates SRD5A1 protein expression in HaCaT cells. SRD5A1-IN-2 reduces dihydrotestosterone (DHT) production in HaCaT cells. SRD5A1-IN-2 can be used for the study of androgen-related conditions such as androgenetic alopecia (AGA) .
Cat. No.: HY-P81206
Synonyms: 3 oxo 5 alpha Steroid 4 dehydrogenase 2 antibody;
3-oxo-5-alpha-Steroid 4-dehydrogenase 2 antibody;
5 alpha SR2 antibody;
5 alpha-SR2 antibody;
5ART2 antibody;
e II 5 alpha reductase antibody;
EC antibody;
MGC138457 antibody;
Micropenis, included antibody;
S5A2_HUMAN antibody;
S5AR 2 antibody;
SR type 2 antibody;
SRD5A2 antibody;
Steroid 5 alpha reductase 2 antibody;
Steroid 5-alpha-reductase 2 antibody;
Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-Steroid delta 4-dehydrogenase alpha 2) antibody;
Type II 5-alpha reductase antibody;
Cat. No.: HY-107385S
Synonyms: ONO-9302-d9; SKF105657-d9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
