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Cat. No.: HY-106363

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MK-0963

(Synonyms: L 654066)

MK-0963 is a steroidal 5α-reductase inhibitor. MK-0963 reduces serum dihydrotestosterone (DHT) concentrations in a dose-dependent manner. MK-0963 can be used for the study of dihydrotestosterone-related diseases such as benign prostate hyperplasia (BPH).

For research use only. We do not sell to patients.

CAS No.: 103497-68-3
Formula: C₂₃H₃₅NO₂
Molecular Weight:357.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

MK-0963 Chemical Structure

CAS No.: 103497-68-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 103497-68-3
Molecular Weight 357.53
Formula C₂₃H₃₅NO₂
SMILES

C[C@@]12[C@](CC[C@@H]2C(CC(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](NC(C=C4)=O)([H])CC3)C)([H])CC1
Synonyms

L 654066
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Depré M, et al. Pharmacodynamics and tolerability of L-654,066, a steroid 5 alpha-reductase inhibitor, in men. Clin Pharmacol Ther. 1992 Oct;52(4):409-12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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