93 Results for "

Streptomyces sp.

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "Streptomyces sp." in MCE Product Catalog:

3
3 Cited Publications
Referencia número: HY-N12257
No. CAS: 27220-57-1
Antimycin A2 is a selective inhibitor of the cytochrome b-c1 complex in the mitochondrial electron transport chain. Antimycin A2 disrupts mitochondrial membrane potential and produces reactive oxygen species (ROS) by inhibiting electron transfer between cytochrome b and c. Antimycin A2 has bactericidal and piscicidal activity, as well as tumor cell growth inhibitory effects, and can induce S-phase cell cycle arrest and apoptosis in HeLa cells. Antimycin A2 is suitable for research of cervical cancer and fisheries management. Antimycin A2 can be naturally isolated from the fermentation products of Streptomyces sp. strains .
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-113542
No. CAS: 100513-53-9
Synonyms: (+)-Blasticidin A
Target:  

Antibiotic Fungal

Áreas de investigación:  

Infection

Blasticidin A ((+)-Blasticidin A) is a tetraamide acid derivative antibiotic produced by Streptomyces griseochromogenes, as well as a selective inhibitor of aflatoxin production. Blasticidin A exhibits antimicrobial activity against yeast. Blasticidin A can be used in research related to aflatoxin contamination (infection by Aspergillus sp.) .
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-125747
No. CAS: 18865-48-0
Pureza:  98.00%
Synonyms: Actinomycin V (purity≥85%)
Áreas de investigación:  

Infection Cancer

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection .
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-130173
No. CAS: 88979-61-7
Pureza:  ≥99.0%
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H +-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .
loading...
    loading...
Referencia número: HY-P2936
No. CAS: 9031-54-3
Target:  

Phospholipase

Áreas de investigación:  

Cardiovascular Disease Infection

Sphingomyelin phosphodiesterase, Streptomyces sp. is a sphingomyelin phosphodiesterase derived from the genus Streptomyces, which cleaves the phosphodiester bond of sphingomyelin. Sphingomyelin phosphodiesterase, Streptomyces sp. catalyzes the hydrolysis of sphingomyelin in micelles, synthetic substrates, erythrocyte ghost membranes and liposomes, as well as the hydrolysis of the substrate HNP. In the presence of Mg 2+ or Mn 2+ , Sphingomyelin phosphodiesterase, Streptomyces sp. induces hemolysis of bovine erythrocytes through the hydrolysis of membrane sphingomyelin .
loading...
    loading...
Referencia número: HY-19828
No. CAS: 142861-00-5
Synonyms: GEX1A
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .
loading...
    loading...
Referencia número: HY-P3263
No. CAS: 39346-34-4
Synonyms: L-Glutamate oxidase
Áreas de investigación:  

Others

Glutamate oxidase (L-Glutamate oxidase) is a FAD-dependent oxidase with high substrate selectivity. Glutamate oxidase catalyzes the oxidative deamination of L-glutamate using O2 to produce α-ketoglutarate (α-KG), NH3, and H2O2. Glutamate oxidase is applicable to research related to the biocatalytic production of α-KG and the analytical detection of L-glutamate .
loading...
    loading...
Referencia número: HY-W102907
No. CAS: 4551-72-8
Áreas de investigación:  

Infection

Pyrrole-2-carboxamide (Compound 26) is a secondary metabolite. Pyrrole-2-carboxamide can be produced by two mangrove-derived actinomycetes Streptomyces sp. WHUA03072 and Streptomyces sp. WHUA03267 .
loading...
    loading...
Referencia número: HY-N12787
No. CAS: 19912-62-0
Target:  

Others

T-Muurolol is a sesquiterpene and can be isolated from Streptomyces sp. M491 .
loading...
    loading...
Referencia número: HY-134090
No. CAS: 51867-94-8
Synonyms: Antibiotic TS 885; NSC 248958
Target:  

Bacterial VSV

Áreas de investigación:  

Infection

9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
loading...
    loading...
Referencia número: HY-W047478
No. CAS: 4630-20-0
Synonyms: NSC 10154
3-Methylcarbazole (NSC 10154) is a carbazole alkaloid with an IC50 of 25 μg/mL against human fibrosarcoma cells. 3-Methylcarbazole inhibits mycelial growth and conidial germination of a variety of phytopathogenic fungi. 3-Methylcarbazole exhibits anti-inflammatory and antitumor activities. 3-Methylcarbazole can be used in studies related to fibrosarcoma, phytopathogenic fungal infections and inflammatory diseases .
loading...
    loading...
Referencia número: HY-N8743
No. CAS: 5654-86-4
Synonyms: A 65190; Cyclo-(leucyl-prolyl)
Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer .
loading...
    loading...
Referencia número: HY-108032
No. CAS: 165542-15-4
Pureza:  ≥95.0%
Synonyms: Pyrostatin A; 5-Hydroxyectoine
Target:  

OGA

Hydroxyectoin (Pyrostatin A) is a competitive inhibitor of GlcNAcase, with the Ki of 1.7 μM .
loading...
    loading...
Referencia número: HY-118331
No. CAS: 107140-30-7
Synonyms: PD 124895; CL-1957E
Target:  

Antibiotic

Áreas de investigación:  

Infection Cancer

Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer .
loading...
    loading...
Referencia número: HY-121071
No. CAS: 91432-48-3
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively .
loading...
    loading...
Referencia número: HY-122955
No. CAS: 227596-81-8
Xanthobaccin A is a potent antibiotic that can be isolated from the culture fluid of Stenotrophomonas sp. strain SB-K88. Xanthobaccin A exhibits activity against fungi and G+ bacteria, induces zoospore immobilization and lysis, inhibits mycelial growth. Xanthobaccin A can be used for the research of beet damping-off disease, bacterial and fungal infection .
loading...
    loading...
Referencia número: HY-125637
No. CAS: 33538-72-6
Synonyms: Aabomycin A2
Áreas de investigación:  

Infection

Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .
loading...
    loading...
Referencia número: HY-N13017
No. CAS: 701915-56-2
Bhimanone is a bioinactive tetralone, which can be isolated from Streptomyces sp. .
loading...
    loading...
Referencia número: HY-N14403
No. CAS: 30954-70-2
Target:  

Cathepsin

6-Hydroxytetrangulol is a CPP32 protease inducer found in Streptomyces sp .
loading...
    loading...
Referencia número: HY-131054
No. CAS: 35906-51-5
Target:  

Antibiotic Bacterial

Áreas de investigación:  

Infection

Cinerubin B, a glycosylated anthracycline antibiotic, is an anticancer agent from Streptomyces sp. SPB74 .
loading...
    loading...