4630-20-0
Chemical Structure
3-Methylcarbazole
Synonym(s): NSC 10154
- CAS No.: 4630-20-0
- Formula:C13H11N
- Molecular Weight:181.24
IUPAC Name: 3-methyl-9H-carbazole
InChIKey: PHKYYUQQYARDIU-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C=C1)NC3=C2C=CC=C3
Biological Activity: 3-Methylcarbazole (NSC 10154) is a carbazole alkaloid with an IC50 of 25 μg/mL against human fibrosarcoma cells. 3-Methylcarbazole inhibits mycelial growth and conidial germination of a variety of phytopathogenic fungi. 3-Methylcarbazole exhibits anti-inflammatory and antitumor activities. 3-Methylcarbazole can be used in studies related to fibrosarcoma, phytopathogenic fungal infections and inflammatory diseases[1][2][3].
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3-Methylcarbazole | 97.78% | 3-Methylcarbazole (NSC 10154) is a carbazole alkaloid with an IC50 of 25 μg/mL against human fibrosarcoma cells. 3-Methylcarbazole inhibits mycelial growth and conidial germination of a variety of phytopathogenic fungi. 3-Methylcarbazole exhibits anti-inflammatory and antitumor activities. 3-Methylcarbazole can be used in studies related to fibrosarcoma, phytopathogenic fungal infections and inflammatory diseases. | ||||||||||||||||||||
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3-Methylcarbazole (Standard) | ≥98% | 3-Methylcarbazole (NSC 10154) Standard is the analytical standard of 3-Methylcarbazole (HY-W047478). This product is intended for research and analytical applications. 3-Methylcarbazole (NSC 10154) is a carbazole alkaloid with an IC50 of 25 μg/mL against human fibrosarcoma cells. 3-Methylcarbazole inhibits mycelial growth and conidial germination of a variety of phytopathogenic fungi. 3-Methylcarbazole exhibits anti-inflammatory and antitumor activities. 3-Methylcarbazole can be used in studies related to fibrosarcoma, phytopathogenic fungal infections and inflammatory diseases. | ||||||||||||||||||||
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Similarity Score 0.84
HY-337983-Bromocarbazole -
Similarity Score 0.83
HY-W106860R9H-Carbazole-3-carbaldehyde (Standard) -
Similarity Score 0.81
HY-N3959Glycozolinine -
Similarity Score 0.81
HY-W1064563-Methoxy-9H-Carbazole -
Similarity Score 0.79
HY-W6472933-Methyl-9H-carbazol-2-ol -
Similarity Score 0.78
HY-W006474γ-Carboline -
Similarity Score 0.76
HY-W008566RNorharmane (Standard) -
Similarity Score 0.75
HY-171481Thio-acridone -
Similarity Score 0.75
HY-W007771RAcridone (Standard) -
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References
- [1]. Cui CB, et al. Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl. J Asian Nat Prod Res. 2002 Dec;4(4):233-41. [Content Brief]
- [2]. Taechowisan T, et al. Antifungal activity of 3-methylcarbazoles from Streptomyces sp. LJK109; an endophyte in Alpinia galangal. Journal of Applied Pharmaceutical Science. 2012 Mar 30(Issue):124-8.
- [3]. Taechowisan T, et al. Anti-inflammatory effect of 3-methylcarbazoles on RAW 2647 cells stimulated with LPS, polyinosinic-polycytidylic acid and Pam3CSK. Adv Microbiol. 2012 Jun 1;2(02):98-103.
