Sphingomyelin phosphodiesterase, Streptomyces sp.
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Sphingomyelin phosphodiesterase, Streptomyces sp. is a sphingomyelin phosphodiesterase derived from the genus Streptomyces, which cleaves the phosphodiester bond of sphingomyelin. Sphingomyelin phosphodiesterase, Streptomyces sp. catalyzes the hydrolysis of sphingomyelin in micelles, synthetic substrates, erythrocyte ghost membranes and liposomes, as well as the hydrolysis of the substrate HNP. In the presence of Mg2+ or Mn2+ , Sphingomyelin phosphodiesterase, Streptomyces sp. induces hemolysis of bovine erythrocytes through the hydrolysis of membrane sphingomyelin.
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- CAS No.: 9031-54-3
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Sphingomyelin phosphodiesterase from *Streptomyces* sp. (15 munits enzyme; 10 min) induces 80%-100% hemolysis and complete SM hydrolysis in intact bovine erythrocytes[2].
Sphingomyelin phosphodiesterase from *Streptomyces* sp. exhibits hydrolytic activity against HNP, with an activity of 0.0026 μmol/min·units[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9031-54-3
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Appearance Solid
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Color White to off-white
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SMILES
[Sphingomyelin phosphodiesterase, Streptomyces sp.]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (263 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Sugimori D, et al. Extracellular production of a sphingomyelinase from Streptomyces griseocarneus using Streptomyces lividans. Biotechnol Lett. 2011;33(4):727-731. [Content Brief]
[2]. Matsuyama H, et al. Alteration in reactivity of sphingomyelinase from Streptomyces sp. modified with a polyethylene glycol derivative. Biol Pharm Bull. 1993;16(2):107-111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sphingomyelin phosphodiesterase, Streptomyces sp. Related Classifications
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