Sphingomyelin phosphodiesterase, Streptomyces sp.

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Sphingomyelin phosphodiesterase, Streptomyces sp. is a sphingomyelin phosphodiesterase derived from the genus Streptomyces, which cleaves the phosphodiester bond of sphingomyelin. Sphingomyelin phosphodiesterase, Streptomyces sp. catalyzes the hydrolysis of sphingomyelin in micelles, synthetic substrates, erythrocyte ghost membranes and liposomes, as well as the hydrolysis of the substrate HNP. In the presence of Mg²⁺or Mn²⁺, Sphingomyelin phosphodiesterase, Streptomyces sp. induces hemolysis of bovine erythrocytes through the hydrolysis of membrane sphingomyelin.

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Sphingomyelin phosphodiesterase, Streptomyces sp. Chemical Structure

CAS No. : 9031-54-3

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10 U		In-stock	Estimated Time of Arrival: December 31

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Other Forms of Sphingomyelin phosphodiesterase, Streptomyces sp.:

Sphingomyelin phosphodiesterase, Bacillus cereus Get quote

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Description	Sphingomyelin phosphodiesterase, Streptomyces sp. is a sphingomyelin phosphodiesterase derived from the genus Streptomyces, which cleaves the phosphodiester bond of sphingomyelin. Sphingomyelin phosphodiesterase, Streptomyces sp. catalyzes the hydrolysis of sphingomyelin in micelles, synthetic substrates, erythrocyte ghost membranes and liposomes, as well as the hydrolysis of the substrate HNP. In the presence of Mg²⁺or Mn²⁺, Sphingomyelin phosphodiesterase, Streptomyces sp. induces hemolysis of bovine erythrocytes through the hydrolysis of membrane sphingomyelin^[1]^[2].
In Vitro	Sphingomyelin phosphodiesterase from Streptomyces sp. (15 munits enzyme; 10 min) induces 80%-100% hemolysis and complete SM hydrolysis in intact bovine erythrocytes^[2]. Sphingomyelin phosphodiesterase from Streptomyces sp. exhibits hydrolytic activity against HNP, with an activity of 0.0026 μmol/min·units^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Sphingomyelin phosphodiesterase, Streptomyces sp. Related Antibodies
CAS No.	9031-54-3
Appearance	Solid
Color	White to off-white
SMILES	[Sphingomyelin phosphodiesterase, Streptomyces sp.]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Select Batch: Data Sheet (263 KB) SDS (251 KB) COA (242 KB) Handling Instructions (2659 KB)
References	[1]. Sugimori D, et al. Extracellular production of a sphingomyelinase from Streptomyces griseocarneus using Streptomyces lividans. Biotechnol Lett. 2011;33(4):727-731. [2]. Matsuyama H, et al. Alteration in reactivity of sphingomyelinase from Streptomyces sp. modified with a polyethylene glycol derivative. Biol Pharm Bull. 1993;16(2):107-111.