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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
TAOK3 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "TAOK3 kinase" in MCE Product Catalog:
Cat. No.: HY-181280
Target:
Research Areas:
VU6083859 is a blood-brain barrier-permeable TAOK1 inhibitor with an IC50 of 158 nM. VU6083859 selectively inhibits TAOK1, exhibits only weak or no activity against TAOK2 and TAOK3, and shows high selectivity for a variety of other kinases. VU6083859 is applicable to research related to neurodevelopmental disorders and tauopathies.
Cat. No.: HY-P77222
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TAOK3; CTCL-Associated Antigen HD-CL-09; TAO kinase 3; kinase From Chicken Homolog A; MAP3K18; Jun kinase-Inhibitory kinase; JIK; JNK/SAPK-Inhibitory kinase; DPK; HKFC-A; Thousand And One Amino Acid Protein 3; Non-Specific Serine/Threonine Protein kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703907
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TAOK3; CTCL-Associated Antigen HD-CL-09; TAO kinase 3; kinase From Chicken Homolog A; MAP3K18; Jun kinase-Inhibitory kinase; JIK; JNK/SAPK-Inhibitory kinase; DPK; HKFC-A; Thousand And One Amino Acid Protein 3; Non-Specific Serine/Threonine Protein kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181619
CAS No.: 3114565-22-6
Target:
Research Areas:
TAO Kinase-IN-3 is a potent pan-TAOK (Thousand-And-One Kinase) inhibitor that specifically binds to and inhibits the kinase activities of TAOK1, TAOK2 and TAOK3 with Kd values of <0.17 nM, 0.34 nM, and 0.17 nM, respectively. TAO Kinase-IN-3 can be used to study Alzheimer's disease, primary tauopathies and related syndromes. In addition, TAO Kinase-IN-3 is also widely used in research on the mechanisms of cancer cachexia and the muscle atrophy it induces .
Cat. No.: HY-181281
Target:
Research Areas:
VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
