60 Results for "

TGF beta 1 Protein

" in MedChemExpress (MCE) Product Catalog:
Products (60)

60 Results for "TGF beta 1 Protein" in MCE Product Catalog:

170
170 Publications Verification
Referencia número: HY-P7118
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
Species:  
Source:  
CHO
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69
69 Cited Publications
Referencia número: HY-P7117
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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57
57 Cited Publications
Referencia número: HY-P70543
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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31
31 Cited Publications
Referencia número: HY-P70648
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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18
18 Cited Publications
Referencia número: HY-P0299
No. CAS: 283609-79-0
Target:  

TGF-β Receptor

Áreas de investigación:  

Cancer

LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier .
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18
18 Cited Publications
Referencia número: HY-P0299A
No. CAS: 2828433-17-4
Target:  

TGF-β Receptor

Áreas de investigación:  

Cancer

LSKL, Inhibitor of Thrombospondin (TSP-1) TFA is a latency-associated protein (LAP)-TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) TFA suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH). LSKL, Inhibitor of Thrombospondin (TSP-1) TFA can readily crosse the blood-brain barrier .
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7
7 Cited Publications
Referencia número: HY-P78168
Pureza:  ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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5
5 Cited Publications
Referencia número: HY-N5124
No. CAS: 60767-80-8
Synonyms: Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside
Meloside A (Isovitexin 2''-O-glucoside) is a flavonoid with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss .
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4
4 Cited Publications
Referencia número: HY-N2259
No. CAS: 19431-84-6
Synonyms: (+)-Curcumenol
Curcumenol ((+)-Curcumenol) is a natural compound with oral efficacy, exhibiting an IC50 of 12.6 μM and a Ki of 10.8 μM against human CYP3A4. Curcumenol inhibits TNFα-induced phosphorylation/degradation of IκBα, phosphorylation/nuclear translocation of NF-κB p65, as well as the upregulation of MMP3, MMP9, MMP13, TRAF3, IL1RL1, TNFα and IL-1β. Curcumenol suppresses LPS-induced phosphorylation of Akt and p38 MAPK, as well as the production of pro-inflammatory mediators/proteins, and downregulates the SLC7A11/NF-κB/TGF-β pathway. Curcumenol binds to and inhibits the activation of Fyn and Lyn, blocks the function of downstream FcεRI signaling components, and reduces the release of allergic mediators/cytokines. Curcumenol upregulates the expression of KDM6B, and promotes chondrocyte proliferation and cartilage repair. Curcumenol induces ferroptosis and apoptosis, regulates the EMT process, and inhibits tumor growth and metastasis of triple-negative breast cancer. Curcumenol possesses anti-inflammatory, neuroprotective, antioxidant, antitumor, antiviral and hepatoprotective activities. Curcumenol can be used in research related to intervertebral disc degeneration, cancer, inflammation, central nervous system neurodegenerative diseases, allergic reactions and knee osteoarthritis .
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3
3 Cited Publications
Referencia número: HY-P78360
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
Species:  
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3
3 Cited Publications
Referencia número: HY-P78213
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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3
3 Cited Publications
Referencia número: HY-P78668
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
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2
2 Cited Publications
Referencia número: HY-B0449
No. CAS: 3963-95-9
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection

Methacycline hydrochloride is a tetracycline antibiotic and can inhibits bacterial protein synthesis. Methacycline hydrochloride is a potent epithelial-mesenchymal transition (EMT) inhibitor. Methacycline hydrochloride blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline hydrochloride is an antimicrobial and has the potential for pulmonary fibrosis .
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2
2 Cited Publications
Referencia número: HY-E70226
No. CAS: 71965-46-3
Synonyms: CTSS
Human Cathepsin S (CTSS) is a cysteine protease with elastinolytic activity. Human Cathepsin S is inhibited by cysteine protease inhibitors such as E-64 (HY-15282) and cystatin C. Human Cathepsin S cleaves substrates including elastin, TGF-β1, Myelin basic protein (HY-P1821), PAR2, SIRT1, collagen 18A1, FKN, and MHC-II invariant chain fragments, thereby driving processes such as elastic matrix degradation, TGF-β1 signaling, demyelination, PAR2-mediated calcium mobilization, NF-κB activation, hepatic fibrosis, immune homeostasis regulation, and antigen presentation. Human Cathepsin S can be used in the research of cardiovascular diseases, chronic kidney diseases, autoimmune diseases, tumors, Alzheimer's disease, and obesity .
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1
1 Cited Publications
Referencia número: HY-124745
No. CAS: 1228280-29-2
Pureza:  99.88%
Target:  

MAP4K Wnt Apoptosis

Áreas de investigación:  

Cancer

KY-05009 is an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM. KY-05009 pharmacologically inhibits TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells. KY-05009 inhibits the protein expression of TNIK and transcriptional activity of Wnt target genes and induces apoptosis in cancer cells. KY-05009 exerts anti-cancer activity .
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1
1 Cited Publications
Referencia número: HY-N6082
No. CAS: 34298-86-7
Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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1
1 Cited Publications
Referencia número: HY-N1956
No. CAS: 7460-43-7
Rubiadin-1-methyl ether is an orally potent NF-κB p65 inhibitor and autophagy inhibitor. Rubiadin-1-methyl ether inhibits RANKL-induced phosphorylation and nuclear translocation of p65, suppresses BECN1 transcription, blocks LC3 conversion and autophagosome formation, thereby reducing the levels of BECN1 mRNA and Beclin1 protein. Rubiadin-1-methyl ether inhibits osteoclastogenesis, cell proliferation, macrophage M2 polarization and the TGF-β1 signaling pathway, and effectively alleviates pulmonary inflammation. Rubiadin-1-methyl ether is widely used in research on osteoporosis, pulmonary fibrosis, idiopathic pulmonary fibrosis, acute lung injury and other related diseases .
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1
1 Cited Publications
Referencia número: HY-P70543G
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
Species:  
Source:  
CHO
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1
1 Cited Publications
Referencia número: HY-P70433
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
Species:  
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1
1 Cited Publications
Referencia número: HY-P73615
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-beta-1; CED; TGF-beta1; Transforming Growth Factor beta-1 ProProtein; IBDIMDE; Prepro-Transforming Growth Factor beta-1;
Species:  
Rat
Source:  
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