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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
TRPM8 receptor agonist
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "TRPM8 receptor agonist" in MCE Product Catalog:
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Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
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1 Cited Publications
Cat. No.: HY-N8264
CAS No.: 73255-40-0
Category:
Natural Products Neurological Disease Moringa oleifera Lam. Moringaceae Plants Disease Research Fields Inflammation/Immunology
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1 Cited Publications
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M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
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1 Cited Publications
Cat. No.: HY-16162A
CAS No.: 1008763-54-9
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D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.
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Other Monoterpenes Terpenoids Other Diseases Plants Lauraceae Disease Research Fields Cinnamomum camphora
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Cat. No.: HY-177763
CAS No.: 2791281-99-5
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TRPM8 receptor agonist-1 (Example 81) is a TRPM8 receptor agonist. TRPM8 receptor agonist-1 can trigger the inward flow of calcium, sodium and other ions within the cell, causing the cell membrane to depolarize and triggering an action potential. TRPM8 receptor agonist-1 can activate signals related to the swallowing reflex and can be used for the research of oropharyngeal dysphagia .
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Cryosim-3 is a selective TRPM8 receptor agonist. Cryosim-3 increases tear secretion and relieves ocular discomfort in animal models .
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FEMA 4809 is a TRPM8 receptor agonist (EC50=0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception .
Cat. No.: HY-16162
CAS No.: 947257-66-1
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D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity.
Synonyms: D-(+)-Camphor (Standard); (1R)-(+)-Camphor (Standard)
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Cat. No.: HY-110181R
CAS No.: 883976-12-3
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M8-B (Standard) is the analytical standard of M8-B (HY-110181). This product is intended for research and analytical applications. M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
Cat. No.: HY-11062R
CAS No.: 36945-98-9
Synonyms: AG-3-5 (Standard)
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Research Areas:
Icilin (Standard) is the analytical standard of Icilin (HY-11062). This product is intended for research and analytical applications. Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
