1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. TRP Channel
  3. D-3263 hydrochloride

D-3263 hydrochloride 

Cat. No.: HY-16162A Purity: 98.01%
Handling Instructions

D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.

For research use only. We do not sell to patients.

D-3263 hydrochloride Chemical Structure

D-3263 hydrochloride Chemical Structure

CAS No. : 1008763-54-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 126 In-stock
Estimated Time of Arrival: December 31
1 mg USD 90 In-stock
Estimated Time of Arrival: December 31
5 mg USD 140 In-stock
Estimated Time of Arrival: December 31
10 mg USD 220 In-stock
Estimated Time of Arrival: December 31
50 mg USD 677 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of D-3263 hydrochloride:

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Description

D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.

In Vitro

D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1]

Molecular Weight

409.95

Formula

C₂₁H₃₂ClN₃O₃

CAS No.

1008763-54-9

SMILES

[H]Cl.O=C1N(CCN)C2=CC(OC)=CC=C2N1C([[email protected]]3[[email protected]](C(C)C)CC[[email protected]@H](C)C3)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 40 mg/mL (97.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4393 mL 12.1966 mL 24.3932 mL
5 mM 0.4879 mL 2.4393 mL 4.8786 mL
10 mM 0.2439 mL 1.2197 mL 2.4393 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.01%

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Product Name:
D-3263 hydrochloride
Cat. No.:
HY-16162A
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