19 Results for "

Thiazolidine

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Thiazolidine" in MCE Product Catalog:

Cat. No.: HY-I0144
CAS No.: 504-78-9
Target:  

Drug Intermediate

Research Areas:  

Others

Thiazolidine is a five-membered heterocyclic compound containing sulfur and nitrogen heteroatoms. Thiazolidine is an important intermediate in organic synthesis. Thiazolidine derivatives possess diverse bioactivities, such as anti-tumor, antibacterial and insecticidal activities, and the capacity to reduce blood glucose levels .
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14
14 Cited Publications
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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2
2 Cited Publications
Cat. No.: HY-B1169
CAS No.: 444-27-9
Synonyms: 1,3-Thiazolidine-4-carboxylic acid
Research Areas:  

Cardiovascular Disease Cancer

Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer .
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Cat. No.: HY-77599
CAS No.: 14446-47-0
Target:  

Drug Intermediate

Research Areas:  

Others

Thiazolidine hydrochloride is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-148332
CAS No.: 118059-38-4
Research Areas:  

Neurological Disease

Z-Thioprolyl-Thiazolidine is a potent and specific prolyl endopeptidase inhibitor with an Ki value of 0.36 nM for bovine brain prolyl endopeptidase
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Cat. No.: HY-B1169R
CAS No.: 444-27-9
Synonyms: 1,3-Thiazolidine-4-carboxylic acid (Standard)
Timonacic (Standard) is the analytical standard of Timonacic. This product is intended for research and analytical applications. Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer .
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Cat. No.: HY-180433
CAS No.: 2377084-09-6
Target:  

Parasite

Research Areas:  

Infection

Sulfiflumin (compound I) is a thiazolidine acaricide. Sulfiflumin can be used as a plant protection agent .
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Cat. No.: HY-175376
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

QPyN16Th is an N-palmitoylated cationic thiazolidine antibiotic. QPyN16Th is selectively active against the Gram-positive bavteria E. faecalis, S. aureus and MRSA with an MIC of 1.95 μM over gram-negative bacteria. QPyN16Th can induce membrane permeabilization and depolarization and ROS production in MRSA. QPyN16Th increases the survival of zebrafish model of intramuscular MRSA infection .
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Cat. No.: HY-109887
CAS No.: 1004550-20-2
Research Areas:  

Others

3-Bromoimidazo[1,2-a]pyridine-6-carbaldehyde is a biochemical reagent that can be used for the preparation of (5Z)-5-[(3-acetylimidazo[1,2-α]pyridin-6-yl) methylidene]-1,3-thiazolidine-2,4-dione .
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Cat. No.: HY-130096
CAS No.: 141534-26-1
Target:  

ADC Linkers

Research Areas:  

Cancer

Ald-Ph-amido-C2-nitrate (Example XXIVb) is a thiazolidine derivative, used as a noncleavable ADC linker .
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Cat. No.: HY-151934
Target:  

Apoptosis

Research Areas:  

Cancer

ERK-IN-6 (compound 6g) is an potent anti-proliferation agent against esophageal squamous cell carcinoma (ESCC). ERK-IN-6 induces cell apoptosis via ERK pathway. ERK-IN-6 can be used for the research of ESCC .
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Cat. No.: HY-131050
CAS No.: 6325-94-6
Target:  

Bacterial Fungal

Research Areas:  

Infection

Aspergillus niger-IN-1 (Compound 17), a derivative of thiazolidine-2,4-dione, acts as an antimicrobial agent. Aspergillus niger-IN-1 exhibited antimicrobial activity against various bacterial and fungal strains, including Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumonia, Escherichia coli, Salmonella typhi, Candida albicans and Aspergillus niger, with MIC values of 11.3, 5.65, 11.3, 5.65, 5.65, 5.65, and 5.65 μM/mL, respectively .
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Cat. No.: HY-W745771
D-Penicillamine-d6 is the deuterium labeled L-Penicillamine (HY-116073). L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5 '-phosphate-thiazolidine adduct. L-Penicillamine is a metal chelating agent of intermediate strength .
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Cat. No.: HY-117047
CAS No.: 1044255-57-3
Target:  

Apoptosis Caspase

Research Areas:  

Cancer

ALC67 is a cytotoxic thiazolidine compound with an IC50 of approximately 5 μM against liver, breast cancer, colon cancer, and endometrial cancer cell lines. ALC67 induces apoptosis in cancer cells by activating caspase-9 and causing cell cycle arrest at the SubG1/G1 phase, via a pathway that is independent of death receptors. ALC67 can be used in cancer research .
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Cat. No.: HY-W722107
CAS No.: 3066050-54-9
Synonyms: 1,3-Thiazolidine-4-carboxylic acid-d4
Timonacic-d4 (1,3-Thiazolidine-4-carboxylic acid-d4) is deuterium labeled Timonacic. Timonacic (1,3-Thiazolidine-4-carboxylic acid) is a thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects, and it can be used to study acute illnesses and liver diseases, by inducing reversal, it is also used in research on certain cancer cases .
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Cat. No.: HY-W114530S
CAS No.: 1217211-89-6
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy-d4)benzylidene)thiazolidine-2,4-dione is the deuterium labeled 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione .
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Cat. No.: HY-W703819
CAS No.: 1794768-28-7
5-Benzyloxy rosiglitazone-d4 is the deuterium labeled 5-(4-(2-((5-(Benzyloxy)pyridin-2-yl)(methyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione (HY-W700248).
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Cat. No.: HY-Y0823
CAS No.: 532-55-8
Research Areas:  

Infection

Benzoyl isothiocyanate is an aromatic isothiocyanate derivative with antibacterial and acaricidal activities. Benzoyl isothiocyanate inhibits the growth of specific oral bacteria, and also serves as an intermediate for the synthesis of heterocyclic compounds such as thiazolidine and quinazoline derivatives. Benzoyl isothiocyanate exhibits acaricidal activity against Dermatophagoides farina (dust mite) and D. pteronyssinus (house dust mite). Benzoyl isothiocyanate can be used in research related to bacterial infection, pest control and organic synthesis .
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