1044255-57-3
1044255-57-3
Chemical Structure
ALC67
- CAS No.: 1044255-57-3
- Formula:C15H15NO3S
- Molecular Weight:289.35
IUPAC Name: ethyl (4R)-2-phenyl-3-propioloylthiazolidine-4-carboxylate
InChIKey: VYDZOJXGXGQPPY-NBFOIZRFSA-N
SMILES: O=C([C@H]1N(C(C#C)=O)C(C2=CC=CC=C2)SC1)OCC
Biological Activity: ALC67 is a cytotoxic thiazolidine compound with an IC50 of approximately 5 μM against liver, breast cancer, colon cancer, and endometrial cancer cell lines. ALC67 induces apoptosis in cancer cells by activating caspase-9 and causing cell cycle arrest at the SubG1/G1 phase, via a pathway that is independent of death receptors. ALC67 can be used in cancer research[1].
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ALC67 | ALC67 is a cytotoxic thiazolidine compound with an IC50 of approximately 5 μM against liver, breast cancer, colon cancer, and endometrial cancer cell lines. ALC67 induces apoptosis in cancer cells by activating caspase-9 and causing cell cycle arrest at the SubG1/G1 phase, via a pathway that is independent of death receptors. ALC67 can be used in cancer research. | |||||||||||||||||||||
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