5 Results for "

Thioguanine

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Thioguanine" in MCE Product Catalog:

14
14 Cited Publications
Cat. No.: HY-13765
CAS No.: 154-42-7
Purity:  99.90%
Synonyms: Thioguanine; 2-Amino-6-purinethiol
6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-D0995
CAS No.: 55727-10-1
Synonyms: MESG
7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be converted to 7-methyl-6-thioguanine in the presence of purine nucleoside phosphorylase and inorganic phosphate. 7-Methyl-6-thioguanosine can be used to quantify inorganic phosphate. 7-Methyl-6-thioguanosine can also be used to determine the activities of purine nucleoside phosphorylase and protein phosphatases .
loading...
    loading...
Cat. No.: HY-13765R
CAS No.: 154-42-7
Synonyms: Thioguanine (Standard); 2-Amino-6-purinethiol (Standard)
6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
loading...
    loading...
Cat. No.: HY-139193
CAS No.: 2567914-01-4
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

TH1760 is an inhibitor of NUDIX-type 15 (NUDT15) with an IC50 value of 25 nM. TH1760 sensitizes cells to 6-thioguanine by enhancing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 enhances the anti-leukemia effect of thiopurine .
loading...
    loading...
Cat. No.: HY-W653745
CAS No.: 1330266-29-9
Synonyms: Thioguanine-13C2,15N; 2-Amino-6-purinethiol-13C2,15N
6-Thioguanine-13C2,15N (Thioguanine-13C2,15N) is the 13C and 15N labeled 6-Thioguanine (HY-13765). 6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
loading...
    loading...