154-42-7
154-42-7
Chemical Structure
6-Thioguanine
Synonym(s): Thioguanine; 2-Amino-6-purinethiol
- CAS No.: 154-42-7
- Formula:C5H5N5S
- Molecular Weight:167.20
IUPAC Name: 2-amino-9H-purine-6-thiol
InChIKey: WYWHKKSPHMUBEB-UHFFFAOYSA-N
SMILES: SC1=NC(N)=NC2=C1N=CN2
Biological Activity: 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6-Thioguanine | 99.54% | 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | ||||||||||||||||||||
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6-Thioguanine (Standard) | 98.41% | 6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | ||||||||||||||||||||
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6-Thioguanine-13C2,15N | 6-Thioguanine-13C2,15N (Thioguanine-13C2,15N) is the 13C and 15N labeled 6-Thioguanine (HY-13765). 6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | |||||||||||||||||||||
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