55727-10-1
Chemical Structure
7-Methyl-6-thioguanosine
Synonym(s): MESG
- CAS. Nr.: 55727-10-1
- Formula:C11H15N5O4S
- Molecular Weight:313.33
IUPAC Name: (2R,3R,4S,5R)-2-(2-amino-7-methyl-6-thioxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-olate
InChIKey: JZOJDNSUWURGIR-KQYNXXCUSA-N
SMILES: S=C1NC(N)=NC2=C1[N+](C)=CN2[C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)[O-]
Biological Activity: 7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be converted to 7-methyl-6-thioguanine in the presence of purine nucleoside phosphorylase and inorganic phosphate. 7-Methyl-6-thioguanosine can be used to quantify inorganic phosphate. 7-Methyl-6-thioguanosine can also be used to determine the activities of purine nucleoside phosphorylase and protein phosphatases[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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7-Methyl-6-thioguanosine | 93.68% | 7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be converted to 7-methyl-6-thioguanine in the presence of purine nucleoside phosphorylase and inorganic phosphate. 7-Methyl-6-thioguanosine can be used to quantify inorganic phosphate. 7-Methyl-6-thioguanosine can also be used to determine the activities of purine nucleoside phosphorylase and protein phosphatases. | ||||||||||||||||||||
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References
- [1]. Cheng Q, et al. A continuous spectrophotometric assay for protein phosphatases. Anal Biochem. 1995 Mar 20;226(1):68-73. [Content Brief]
- [2]. Anna-Maja Aberg, et al. Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Scand J Clin Lab Invest. 2010 Feb;70(1):8-14. [Content Brief]
