Tissue Transglutaminase

By Targets:	Transglutaminase (1) Biochemical Assay Reagents (2) Endogenous Metabolite (3) FAK (1) Glutaminase (3) Integrin (1) JAK (2) PROTACs (1) RAR/RXR (1) Reference Standards (1) Src (1)
By Research Areas:	Cancer (7) Metabolic Disease (4) Neurological Disease (3)

Targets Recommended: Transglutaminase Tissue Factor Pathway Inhibitor (TFPI) MALT1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12589

ZM39923 hydrochloride 2 Publications Verification	JAK	Neurological Disease Cancer
ZM39923 hydrochloride is a JAK3 inhibitor, with a pIC₅₀ of 7.1; ZM39923 hydrochloride also potently inhibits tissue transglutaminase (TGM2) with an IC₅₀ of 10 nM.

HY-Y1365C

Fish Gelatin,suitable for cell culture	Biochemical Assay Reagents	Others
Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

HY-113089

Epsilon-(gamma-glutamyl)-lysine H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys	Endogenous Metabolite	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113089A

Epsilon-(gamma-glutamyl)-lysine TFA H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA	Endogenous Metabolite	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-128595

MT-4	Transglutaminase	Cancer
MT-4 is a derivative of a tissue *transglutaminase* (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel.

HY-E70437

Guinea pig liver transglutaminase Tissue-type Transglutaminase; TG2; TGase 2	Biochemical Assay Reagents	Others
Guinea pig liver transglutaminase (Tissue-type transglutaminase) is an exoenzyme. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-102073

TG53	Glutaminase Integrin FAK Src	Cancer
TG53 is a potent inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. TG53 inhibits formation of a complex with integrin β1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research .

HY-113089AR

Epsilon-(gamma-glutamyl)-lysine TFA (Standard) H-Glu(H-Lys-OH)-OH TFA (Standard); γ-Glu-ε-Lys TFA (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-155643

PROTAC TG2 degrader-1	PROTACs Glutaminase	Cancer
PROTAC TG2 degrader-1 (compound 11) is a von Hippel-Lindau (VHL)-based PROTAC targeting tissue transglutaminase (TG2) with a K_D of 68.9 μM. PROTAC TG2 degrader-1 reduces TG2 in ovarian cancer cells in a proteasome-dependent manner .

HY-12589A

ZM39923	JAK	Neurological Disease Cancer
ZM39923 is a JAK3 inhibitor, with a pIC₅₀ of 7.1; ZM39923 also potently inhibits tissue transglutaminase (TGM2) with an IC₅₀ of 10 nM.

HY-123933

TTGM 5826	Glutaminase	Neurological Disease Cancer
TTGM 5826 is a tissue transglutaminase (tTG) inhibitor with an EC₅₀ of 20 μM. TTGM 5826 stabilizes the open conformation of tTG that exhibits protein cross-linking activity, and acts as a competitive inhibitor of tTG-mediated cross-linking activity. TTGM 5826 inhibits the transformed phenotypes of breast cancer cells, brain cancer cells and glioma stem cells. TTGM 5826 can be used in the research of breast cancer, glioblastoma, pancreatic cancer and glioma stem cell-related tumors .

HY-167262

AGN-191659	RAR/RXR	Metabolic Disease Cancer
AGN-191659 is an orally active RAR/RXR agonist with EC₅₀ values of 11 nM, 23 nM, and 37 nM for RXRα, RARβ, and RARγ, respectively. AGN-191659 activates RXRα, RARβ and RARγ to induce gene transcription. AGN-191659 induces tissue transglutaminase activity, inhibits ornithine decarboxylase activity induced by tumor promoters, and suppresses chondrogenesis. AGN-191659 reverses basic fibroblast growth factor-induced endothelial cell proliferation. AGN-191659 induces hypertriglyceridemia in rat models. AGN-191659 inhibits total heparin-releasable lipase activity. AGN-191659 can be used in research related to promyelocytic leukemia and hypertriglyceridemia .

Cat. No.	Product Name	Type

HY-Y1365C

Fish Gelatin,suitable for cell culture	Biochemical Assay Reagents
Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

Fish Gelatin,suitable for cell culture

Biochemical Assay Reagents

Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

Cat. No.	Product Name	Target	Research Area

HY-113089

Epsilon-(gamma-glutamyl)-lysine H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys	Endogenous Metabolite	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113089A

Epsilon-(gamma-glutamyl)-lysine TFA H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA	Endogenous Metabolite	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113089AR

Epsilon-(gamma-glutamyl)-lysine TFA (Standard) H-Glu(H-Lys-OH)-OH TFA (Standard); γ-Glu-ε-Lys TFA (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113089

Epsilon-(gamma-glutamyl)-lysine H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113089A

Epsilon-(gamma-glutamyl)-lysine TFA H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113089AR

Epsilon-(gamma-glutamyl)-lysine TFA (Standard) H-Glu(H-Lys-OH)-OH TFA (Standard); γ-Glu-ε-Lys TFA (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71132A

	TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue Transglutaminase; Transglutaminase C; TGase-2	Mouse	HEK293
	The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis.TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways.TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by HEK293 , with C-10*His labeled tag.

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Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) IP (2) WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

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HY-P82510

	Transglutaminase 2 Antibody (YA2255) TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue Transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2	WB, IHC-P, IP	Human, Mouse, Rat
	Transglutaminase 2 Antibody (YA2255) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transglutaminase 2.

HY-P82510A

	Transglutaminase 2 Antibody (YA2255)(PBS only) TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue Transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2	WB, IHC-P, IP	Human, Mouse, Rat
	Transglutaminase 2 Antibody (YA2255) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transglutaminase 2.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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Tissue Transglutaminase

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