2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Epsilon-(gamma-glutamyl)-lysine

Epsilon-(gamma-glutamyl)-lysine  (Synonyms: H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys)

Cat. No.: HY-113089 Purity: 99.90%
COA
SDS
Handling Instructions Technical Support

Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration.

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Epsilon-(gamma-glutamyl)-lysine

Epsilon-(gamma-glutamyl)-lysine 화학구조

CAS No. : 17105-15-6

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of Epsilon-(gamma-glutamyl)-lysine:

Epsilon-(gamma-glutamyl)-lysine Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].
IC50 & Target

Human Endogenous Metabolite

 

분자량

275.30

화학식

C11H21N3O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCC(NCCCC[C@H](N)C(O)=O)=O)=O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

DMSO : 50 mg/mL (181.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6324 mL 18.1620 mL 36.3240 mL
5 mM 0.7265 mL 3.6324 mL 7.2648 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.90%

SDS (252 KB)

COA (242 KB) HNMR (261 KB) RP-HPLC (207 KB) MS (227 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6324 mL 18.1620 mL 36.3240 mL 90.8100 mL
5 mM 0.7265 mL 3.6324 mL 7.2648 mL 18.1620 mL
10 mM 0.3632 mL 1.8162 mL 3.6324 mL 9.0810 mL
15 mM 0.2422 mL 1.2108 mL 2.4216 mL 6.0540 mL
20 mM 0.1816 mL 0.9081 mL 1.8162 mL 4.5405 mL
25 mM 0.1453 mL 0.7265 mL 1.4530 mL 3.6324 mL
30 mM 0.1211 mL 0.6054 mL 1.2108 mL 3.0270 mL
40 mM 0.0908 mL 0.4541 mL 0.9081 mL 2.2703 mL
50 mM 0.0726 mL 0.3632 mL 0.7265 mL 1.8162 mL
60 mM 0.0605 mL 0.3027 mL 0.6054 mL 1.5135 mL
80 mM 0.0454 mL 0.2270 mL 0.4541 mL 1.1351 mL
100 mM 0.0363 mL 0.1816 mL 0.3632 mL 0.9081 mL
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Epsilon-(gamma-glutamyl)-lysine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epsilon-(gamma-glutamyl)-lysine17105-15-6H-Glu(H-Lys-OH)-OH γ-Glu-ε-LysEndogenous MetaboliteDiabetic nephropathyextracellularmatrixECMfailed blebs,?trabeculectomy modelParkinson's diseaseInhibitorinhibitorinhibit

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상품명:
Epsilon-(gamma-glutamyl)-lysine
Cat. No.:
HY-113089
수량:
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