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Verapamil

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin Receptor (1) Apoptosis (8) Arrestin (1) Biochemical Assay Reagents (1) Calcium Channel (24) Cytochrome P450 (8) Drug Metabolite (4) Fluorescent Dye (1) Isotope-Labeled Compounds (14) Leukotriene Receptor (3) Neurokinin Receptor (1) P-glycoprotein (24) Parasite (2) Phytohormone (1) Potassium Channel (2) Reference Standards (4) Somatostatin Receptor (1) Thrombin (1) YAP (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (19) Infection (3) Inflammation/Immunology (2) Metabolic Disease (9) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14275

*Verapamil* Maximum Cited Publications 86 Publications Verification (±)-Verapamil; CP-16533-1	Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Metabolic Disease Cancer
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-A0064

Verapamil hydrochloride Maximum Cited Publications 86 Publications Verification (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride	Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Cancer
Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-135336

*(R)-Verapamil* hydrochloride** (R)-(+)-Verapamil hydrochloride	P-glycoprotein Apoptosis Calcium Channel	Infection Metabolic Disease
(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an orally active P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport. (R)-Verapamil hydrochloride induces Apoptosis and inhibits L-type calcium channels BZPcc, DHPcc and PLLcc. (R)-Verapamil hydrochloride has anti-septic shock and anti-diabetic effects .

HY-135336A

*(S)-Verapamil* hydrochloride** (S)-(-)-Verapamil hydrochloride	P-glycoprotein Leukotriene Receptor Calcium Channel Apoptosis	Cancer
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .

HY-100750

Norverapamil hydrochloride 1 Publications Verification (±)-NorVerapamil hydrochloride; D591 hydrochloride	Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-P1636

Hirudin (54-65)	Thrombin YAP Calcium Channel	Metabolic Disease
Hirudin (54-65) is a thrombin antagonist and YAP suppressor with anticoagulatory properties.Hirudin (54-65) blocks thrombin's anion binding site, acts on soluble and thrombus-bound thrombin.Hirudin (54-65) suppresses thrombin-induced profibrotic YAP activity, reduces YAP expression, nuclear translocation, and downstream effector signaling in vascular endothelial cells.Hirudin (54-65) ameliorates obstructive cholestasis, attenuates liver fibrosis symptoms, fibrosis-associated angiogenesis, and endothelial-to-mesenchymal transition.Hirudin (54-65) reduces liver inflammation and tissue hypoxia.Hirudin (54-65) promotes extracellular calcium influx through L-type calcium channels in canine coronary artery smooth muscle, mediates contraction.Hirudin (54-65) induces endothelium-independent contraction of canine coronary arterial segments; this response is not affected by indomethacin pretreatment.Hirudin (54-65) can be used for the research of liver obstructive cholestasis, liver fibrosis .

HY-N6015

Bacopasaponin C	Parasite P-glycoprotein	Infection Cancer
Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC₅₀ of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani .

HY-A0064R

Verapamil hydrochloride (Standard) (±)-Verapamil hydrochloride (Standard); CP-16533-1 hydrochloride (Standard)	Reference Standards Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease Cancer
Verapamil (hydrochloride) (Standard) is the analytical standard of Verapamil (hydrochloride). This product is intended for research and analytical applications. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-A0064S

Verapamil-d3 hydrochloride (±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride	Isotope-Labeled Compounds Calcium Channel P-glycoprotein Cytochrome P450	Cardiovascular Disease
Verapamil-d₃ (hydrochloride) is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14276A

Gallopamil hydrochloride MethoxyVerapamil hydrochloride	Calcium Channel	Cardiovascular Disease
Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist . Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC₅₀ of 10.9 μM . Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent .

HY-136589

Verapamil EP Impurity C hydrochloride NSC-609249 hydrochloride	Calcium Channel P-glycoprotein Cytochrome P450	Metabolic Disease
NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor .

HY-14275R

Verapamil (Standard) (±)-Verapamil (Standard); CP-16533-1 (Standard)	Calcium Channel P-glycoprotein Cytochrome P450 Reference Standards	Cardiovascular Disease Metabolic Disease Cancer
Verapamil (Standard) is the analytical standard of Verapamil. This product is intended for research and analytical applications. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-Z15823

(R)-Verapamil DexVerapamil	Calcium Channel Potassium Channel Somatostatin Receptor Arrestin Apoptosis P-glycoprotein	Metabolic Disease Inflammation/Immunology
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil (HY-14275). (R)-Verapamil has a relatively low affinity for L-type calcium channels (Ca_v1.2) (IC₅₀ > 300 μM), and its IC₅₀ for sodium channels (sodium channel) is 3.19 μM. (R)-Verapamil exhibits SSTR2 agonistic activity, with an EC₅₀ of 1.3 μM. (R)-Verapamil significantly downregulates the expression of TXNIP protein in diabetic mouse models and significantly inhibits β-cell apoptosis (apoptosis), effectively controlling blood sugar. (R)-Verapamil can be used as a PET tracer for the function of P-glycoprotein (P-gp) .

HY-D1609

*BODIPY FL Verapamil* hydrochloride**	Fluorescent Dye	Others
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .

HY-14276

Gallopamil MethoxyVerapamil	Calcium Channel	Cardiovascular Disease
Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist . Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC₅₀ of 10.9 μM . Gallopamil is a potent antiarrhythmic and vasodilator agent .

HY-W013727

UK-78282 hydrochloride	Potassium Channel	Inflammation/Immunology
UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC₅₀ of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil .

HY-N8628

3,4,5-Triiodobenzoic acid 3,4,5-TIBA	Phytohormone	Others
3,4,5-Triiodobenzoic acid is an auxin transport inhibitor. 3,4,5-Triiodobenzoic acid stimulates specific [ ³H]verapamil binding to zucchini microsomes. 3,4,5-Triiodobenzoic acid also increases specific [ ³H]verapamil binding to rabbit skeletal muscle membranes. 3,4,5-Triiodobenzoic acid can be used in the research of smooth muscle contraction .

HY-135328AS

Norverapamil-d7 hydrochloride (±)-NorVerapamil-d7 hydrochloride; D591-d7 hydrochloride	Isotope-Labeled Compounds Calcium Channel	Cardiovascular Disease
Norverapamil-d₇ (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-123384

KR30031	P-glycoprotein	Cardiovascular Disease Cancer
KR30031, a Verapamil (HY-14275) analog, is an orally active P-glycoprotein (P-gp) inhibitor. KR30031 enhances the cytotoxicity of anticancer agents by inhibiting P-gp with fewer cardiovascular adverse effects. KR30031 can be used to study multidrug resistance (MDR) reversal in cancer .

HY-10050

CJ-17493	Neurokinin Receptor	Neurological Disease
CJ-17493 is a neurokinin-1 (NK1) receptor antagonist, with a K_i of 0.2 nM. CJ-17493 shows moderate affinity for the verapamil-binding site of L-type Ca ²⁺ channels (IC₅₀ = 164 nM) and site 2 of sodium channels (IC₅₀ = 48 nM). CJ-17493 can be used for the study of neurological diseases .

HY-135336AS

*(S)-Verapamil-d7 hydrochloride* (S)-(-)-Verapamil D7 hydrochloride	Isotope-Labeled Compounds Leukotriene Receptor Calcium Channel Apoptosis	Cancer
(S)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .

HY-135336S

*(R)-Verapamil-d7 hydrochloride* (R)-(+)-Verapamil D7 hydrochloride	P-glycoprotein Isotope-Labeled Compounds Apoptosis	Cancer
(R)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .

HY-135336AS1

*(S)-Verapamil* hydrochloride-d6** (S)-(-)-Verapamil hydrochloride-d6	Isotope-Labeled Compounds Apoptosis Leukotriene Receptor Calcium Channel	Cancer
(S)-Verapamil-d₆ ((S)-(-)-Verapamil-d₆) hydrochloride is the deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .

HY-N13388

5-Hydroxytryptophol-O-glucuronide UGT1A6	Biochemical Assay Reagents	Others
5-Hydroxytryptophol-O-glucuronide is an authentic glucuronide standard and probe metabolite. 5-Hydroxytryptophol-O-glucuronide is used to detect the activity of human UGT1A6 in in vitro systems including human liver microsomes and recombinant UGT1A6 .

HY-A0064S1

Verapamil-d6 hydrochloride (±)-Verapamil-d6 hydrochloride; CP-16533-1-d6 hydrochloride	Isotope-Labeled Compounds	Cardiovascular Disease
Verapamil-d₆ (CP-16533-1-d₆) hydrochloride is the deuterium labled Verapamil (hydrochloride) (HY-A0064). Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-W702292

*(R)-(+)-Verapamil-d6 hydrochloride*	Isotope-Labeled Compounds Apoptosis P-glycoprotein	Cancer
(R)-(+)-Verapamil-d₆ (hydrochloride) is deuterium labeled (R)-Verapamil (hydrochloride). (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .

HY-14275S

Verapamil-d3 (±)-Verapamil-d₃; CP-16533-1-d₃	Isotope-Labeled Compounds Calcium Channel Cytochrome P450 P-glycoprotein	Cardiovascular Disease Metabolic Disease Cancer
Verapamil-d₃ ((±)-Verapamil-d₃) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14275S2

Verapamil-d6 (±)-Verapamil-d₆; CP-16533-1-d₆	Isotope-Labeled Compounds	Cardiovascular Disease Metabolic Disease Cancer
Verapamil-d₆ ((±)-Verapamil-d₆) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-135336BS

*(Rac)-Verapamil-d7 hydrochloride*	Apoptosis P-glycoprotein Isotope-Labeled Compounds	Others
(Rac)-Verapamil-d₇ (hydrochloride) is the deuterium labeled (Rac)-Verapamil .

HY-14275S1

Verapamil-d7 (±)-Verapamil-d₇; CP-16533-1-d₇	Isotope-Labeled Compounds Calcium Channel P-glycoprotein Cytochrome P450	Metabolic Disease Cancer
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-159090

AT1R antagonist 3	Calcium Channel Angiotensin Receptor	Cardiovascular Disease
AT1R antagonist 3 (Compound 1) is an antagonist for angiotensin II type 1 receptor (AT1R) and an inhibitor for calcium channel type-L CaV_1.2 (IC₅₀=0.57 μM). AT1R antagonist 3 exhibits vasodilation efficacy in solated rat aorta (10 μM, 88.7%) and antihypertensive efficacy in rat models .

HY-135328

Norverapamil (±)-NorVerapamil; D591	Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-135328S

Norverapamil-d7 (±)-NorVerapamil-d₇; D591-d₇	Isotope-Labeled Compounds Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-106682

Falipamil AQ-A 39	Calcium Channel	Cardiovascular Disease
Falipamil (AQ-A 39), a calcium channel blocker, is a bradycardic agent. The bradycardic effect results from a reduction in the diastolic depolarization rate and a prolongation of the action potential duration .

HY-100750R

Norverapamil hydrochloride (Standard) (±)-NorVerapamil hydrochloride (Standard); D591 hydrochloride (Standard)	Reference Standards Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil (hydrochloride) (Standard) is the analytical standard of Norverapamil (hydrochloride). This product is intended for research and analytical applications. Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-W699430

Norverapamil-d6 hydrochloride (±)-NorVerapamil-d6 hydrochloride; D591-d6 hydrochloride	Isotope-Labeled Compounds P-glycoprotein Calcium Channel	Cardiovascular Disease
Norverapamil-d₆ ((±)-Norverapamil-d₆) hydrochloride is deuterium labeled Norverapamil (hydrochloride). Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-N7305

Jatrophane 5	P-glycoprotein	Cancer
Jatrophane 5 is a natural product of Jatropha carcas L. Jatrophane 5 has powerful inhibition of P-gp, higher than R(+)-verapamil (HY-14275) and Tariquidar (HY-10550) in colorectal multi-drug resistant cells (DLD1-TxR) .

HY-N6015R

Bacopasaponin C (Standard)	Reference Standards Parasite P-glycoprotein	Infection Cancer
Bacopasaponin C (Standard) is the analytical standard of Bacopasaponin C (HY-N6015). This product is intended for research and analytical applications. Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC₅₀ of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani .

HY-136907S

*(S)-(-)-Verapamil-d3 hydrochloride*	Isotope-Labeled Compounds	Others
(S)-(-)-Verapamil-d₃ (hydrochloride) is the deuterium labeled (S)-(-)-Verapamil hydrochloride .

HY-180282

P-gp-IN-33	P-glycoprotein	Cancer
P-gp-IN-33 (Compound 17a) is a P-gp inhibitor. P-gp-IN-33 binds the Verapamil (HY-14275)-binding pocket of P-gp. P-gp-IN-33 shows higher cytotoxicity against resistant non-small cell lung carcinoma cells than against non-resistant non-small cell lung carcinoma cells .

*BODIPY FL Verapamil* hydrochloride**	Fluorescent Dye
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .

Cat. No.	Product Name	Target	Research Area

HY-P1636

Hirudin (54-65)	Thrombin YAP Calcium Channel	Metabolic Disease
Hirudin (54-65) is a thrombin antagonist and YAP suppressor with anticoagulatory properties.Hirudin (54-65) blocks thrombin's anion binding site, acts on soluble and thrombus-bound thrombin.Hirudin (54-65) suppresses thrombin-induced profibrotic YAP activity, reduces YAP expression, nuclear translocation, and downstream effector signaling in vascular endothelial cells.Hirudin (54-65) ameliorates obstructive cholestasis, attenuates liver fibrosis symptoms, fibrosis-associated angiogenesis, and endothelial-to-mesenchymal transition.Hirudin (54-65) reduces liver inflammation and tissue hypoxia.Hirudin (54-65) promotes extracellular calcium influx through L-type calcium channels in canine coronary artery smooth muscle, mediates contraction.Hirudin (54-65) induces endothelium-independent contraction of canine coronary arterial segments; this response is not affected by indomethacin pretreatment.Hirudin (54-65) can be used for the research of liver obstructive cholestasis, liver fibrosis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6015

Bacopasaponin C	Triterpenes Classification of Application Fields Terpenoids Scrophulariaceae Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst. Source Classification Cancer	Parasite P-glycoprotein
Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC₅₀ of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani .

HY-N13388

5-Hydroxytryptophol-O-glucuronide UGT1A6	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents
5-Hydroxytryptophol-O-glucuronide is an authentic glucuronide standard and probe metabolite. 5-Hydroxytryptophol-O-glucuronide is used to detect the activity of human UGT1A6 in in vitro systems including human liver microsomes and recombinant UGT1A6 .

HY-N7305

Jatrophane 5	Terpenoids Euphorbia peplus Linn. Diterpenoids Euphorbiaceae Plants Source Classification	P-glycoprotein
Jatrophane 5 is a natural product of Jatropha carcas L. Jatrophane 5 has powerful inhibition of P-gp, higher than R(+)-verapamil (HY-14275) and Tariquidar (HY-10550) in colorectal multi-drug resistant cells (DLD1-TxR) .

HY-N6015R

Bacopasaponin C (Standard)	Triterpenes Structural Classification Terpenoids Scrophulariaceae Plants Bacopa monnieri (Linn.) Wettst. Source Classification	Reference Standards Parasite P-glycoprotein
Bacopasaponin C (Standard) is the analytical standard of Bacopasaponin C (HY-N6015). This product is intended for research and analytical applications. Bacopasaponin C is an orally active natural glycoside. Bacopasaponin C can be isolated from Bacopa monniera. Bacopasaponin C inhibits Verapamil (HY-14275)-stimulated P-gp ATPase activity with an IC₅₀ of 57.83 μg/mL. Bacopasaponin C has antitumor activity against sarcomas. Bacopasaponin C has antiparasitic activity against Leishmania donovani .

Cat. No.	Product Name	Chemical Structure

HY-A0064S

Verapamil-d3 hydrochloride

Verapamil-d₃ (hydrochloride) is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-135328AS

Norverapamil-d7 hydrochloride
Norverapamil-d₇ (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-135336AS

*(S)-Verapamil-d7 hydrochloride*
(S)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .

HY-135336S

*(R)-Verapamil-d7 hydrochloride*
(R)-Verapamil-d₇ (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .

HY-135336AS1

*(S)-Verapamil* hydrochloride-d6**
(S)-Verapamil-d₆ ((S)-(-)-Verapamil-d₆) hydrochloride is the deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .

HY-A0064S1

Verapamil-d6 hydrochloride

Verapamil-d₆ (CP-16533-1-d₆) hydrochloride is the deuterium labled Verapamil (hydrochloride) (HY-A0064). Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .

HY-W702292

*(R)-(+)-Verapamil-d6 hydrochloride*
(R)-(+)-Verapamil-d₆ (hydrochloride) is deuterium labeled (R)-Verapamil (hydrochloride). (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .

HY-14275S

Verapamil-d3
Verapamil-d₃ ((±)-Verapamil-d₃) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-14275S2

Verapamil-d6
Verapamil-d₆ ((±)-Verapamil-d₆) is deuterium labeled Verapamil. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-135336BS

*(Rac)-Verapamil-d7 hydrochloride*
(Rac)-Verapamil-d₇ (hydrochloride) is the deuterium labeled (Rac)-Verapamil .

HY-14275S1

Verapamil-d7
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-135328S

Norverapamil-d7
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-W699430

Norverapamil-d6 hydrochloride
Norverapamil-d₆ ((±)-Norverapamil-d₆) hydrochloride is deuterium labeled Norverapamil (hydrochloride). Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-136907S

*(S)-(-)-Verapamil-d3 hydrochloride*
(S)-(-)-Verapamil-d₃ (hydrochloride) is the deuterium labeled (S)-(-)-Verapamil hydrochloride .

Cat. No.	Product Name		Classification

HY-135328AS

Norverapamil-d7 hydrochloride (±)-NorVerapamil-d7 hydrochloride; D591-d7 hydrochloride		Alkynes
Norverapamil-d₇ (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

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