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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
Verapamil
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "Verapamil" in MCE Product Catalog:
91
91 Publications Verification
Synonyms: (±)-Verapamil; CP-16533-1
Research Areas:
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .
91
91 Publications Verification
Synonyms: (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride
Research Areas:
Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .
2
2 Cited Publications
Synonyms: (±)-NorVerapamil hydrochloride; D591 hydrochloride
Research Areas:
Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .
1
1 Cited Publications
Cat. No.: HY-N6015
CAS No.: 178064-13-6
Category:
Triterpenes Terpenoids Scrophulariaceae Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst. Cancer
Target:
Synonyms: (R)-(+)-Verapamil hydrochloride
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Research Areas:
(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an orally active P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport. (R)-Verapamil hydrochloride induces Apoptosis and inhibits L-type calcium channels BZPcc, DHPcc and PLLcc. (R)-Verapamil hydrochloride has anti-septic shock and anti-diabetic effects .
Synonyms: (S)-(-)-Verapamil hydrochloride
Research Areas:
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
Cat. No.: HY-P1636
CAS No.: 113274-56-9
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Synonyms: (±)-Verapamil hydrochloride (Standard); CP-16533-1 hydrochloride (Standard)
Research Areas:
Verapamil (hydrochloride) (Standard) is the analytical standard of Verapamil (hydrochloride). This product is intended for research and analytical applications. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research .
Cat. No.: HY-A0064S
CAS No.: 2714485-49-9
Synonyms: (±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride
Synonyms: MethoxyVerapamil hydrochloride
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Gallopamil hydrochloride (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist . Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM . Gallopamil hydrochloride is a potent antiarrhythmic and vasodilator agent .
Synonyms: NSC-609249 hydrochloride
Research Areas:
NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor .
Research Areas:
Verapamil (Standard) is the analytical standard of Verapamil. This product is intended for research and analytical applications. Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .
Cat. No.: HY-Z15823
CAS No.: 38321-02-7
Synonyms: DexVerapamil
Research Areas:
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil (HY-14275). (R)-Verapamil has a relatively low affinity for L-type calcium channels (Cav1.2) (IC50 > 300 μM), and its IC50 for sodium channels (sodium channel) is 3.19 μM. (R)-Verapamil exhibits SSTR2 agonistic activity, with an EC50 of 1.3 μM. (R)-Verapamil significantly downregulates the expression of TXNIP protein in diabetic mouse models and significantly inhibits β-cell apoptosis (apoptosis), effectively controlling blood sugar. (R)-Verapamil can be used as a PET tracer for the function of P-glycoprotein (P-gp) .
Cat. No.: HY-D1609
CAS No.: 216571-88-9
Cat. No.: HY-14276
CAS No.: 16662-47-8
Synonyms: MethoxyVerapamil
Target:
Research Areas:
Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist . Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM . Gallopamil is a potent antiarrhythmic and vasodilator agent .
Cat. No.: HY-W013727
CAS No.: 136647-02-4
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Research Areas:
UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil .
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3,4,5-Triiodobenzoic acid is an auxin transport inhibitor. 3,4,5-Triiodobenzoic acid stimulates specific [ 3H]verapamil binding to zucchini microsomes. 3,4,5-Triiodobenzoic acid also increases specific [ 3H]verapamil binding to rabbit skeletal muscle membranes. 3,4,5-Triiodobenzoic acid can be used in the research of smooth muscle contraction .
Synonyms: (±)-NorVerapamil-d7 hydrochloride; D591-d7 hydrochloride
Cat. No.: HY-123384
CAS No.: 205535-74-6
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KR30031, a Verapamil (HY-14275) analog, is an orally active P-glycoprotein (P-gp) inhibitor. KR30031 enhances the cytotoxicity of anticancer agents by inhibiting P-gp with fewer cardiovascular adverse effects. KR30031 can be used to study multidrug resistance (MDR) reversal in cancer .
Cat. No.: HY-10050
CAS No.: 225655-10-7
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CJ-17493 is a neurokinin-1 (NK1) receptor antagonist, with a Ki of 0.2 nM. CJ-17493 shows moderate affinity for the verapamil-binding site of L-type Ca 2+ channels (IC50 = 164 nM) and site 2 of sodium channels (IC50 = 48 nM). CJ-17493 can be used for the study of neurological diseases .
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Protocols
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