1 Result for "

Viloxazin (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Viloxazin (Standard)" in MCE Product Catalog:

Cat. No.: HY-W380450R
CAS No.: 46817-91-8
Synonyms: Viloxazin (Standard); Emovit (Standard)
Research Areas:  

Neurological Disease

Viloxazine is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor (IC50= 0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors (Ki=4.2 μM) and agonizes 5-HT2C receptors (EC50= 32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) .
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