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alkynes

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2451

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194

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184

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1839

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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14197A
    Clorgyline hydrochloride
    5+ Cited Publications

    		 Monoamine Oxidase Metabolic Disease
    Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research, structurally related to Pargyline (HY-A0091A). Clorgyline hydrochloride has little effect on the amounts of conjugated dopamine (DA) present in superfusate of slices from rat striatum. Clorgyline hydrochloride contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    Clorgyline hydrochloride
  • HY-140345
    L-Homopropargylglycine
    2 Publications Verification

    		 PROTAC Linkers Cancer
    L-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor .
    L-Homopropargylglycine
  • HY-140922
    Biotin-PEG4-alkyne
    2 Publications Verification

    		 PROTAC Linkers Cancer
    Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG4-alkyne
  • HY-D1314
    FAM azide, 6-isomer

    6-FAM azide

    		 Fluorescent Dye Others
    FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .
    FAM azide, 6-isomer
  • HY-D1269
    Rhodamine-N3 chloride
    1 Publications Verification

    		 Fluorescent Dye Others
    Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups . Rhodamine-N3 chloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 544/576 nm).
    Rhodamine-N3 chloride
  • HY-151705
    Alkyne Cholesterol
    2 Publications Verification

    		 Liposome Metabolic Disease
    Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .
    Alkyne Cholesterol
  • HY-140345A
    L-Homopropargylglycine hydrochloride
    2 Publications Verification

    		 PROTAC Linkers Cancer
    L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor .
    L-Homopropargylglycine hydrochloride
  • HY-P6438
    Alkyne-cRGD

    		Integrin Others Cancer
    Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction .
    Alkyne-cRGD
  • HY-D1588
    BODIPY-X-Alkyne

    		Fluorescent Dye Others
    BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .
    BODIPY-X-Alkyne
  • HY-151645
    Alkyne-SNAP

    		ADC Linker Others
    Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
    Alkyne-SNAP
  • HY-147084
    KY371

    		ADC Linker Metabolic Disease Cancer
    KY371 is a click chemistry reagent containing an alkyne group. KY371 is a broad-range glycosidase inhibitor. KY371 can combine with proteomic analysis of targeted protein to study glycosidases .
    KY371
  • HY-160893
    PSMA-azide

    		PSMA Cancer
    PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups .
    PSMA-azide
  • HY-151646
    Alkyne-PEG5-SNAP

    Alkyne-PEG5-BG

    		 ADC Linker Others
    Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-PEG5-SNAP
  • HY-151680
    TAMRA alkyne, 6-isomer

    		DNA Stain Others
    TAMRA alkyne, 6-isomer is a linker of TAMRA.
    TAMRA alkyne, 6-isomer
  • HY-151688
    6-O-Propynyl-2'-deoxyguanosine

    		ADC Linker Others
    6-O-Propynyl-2'-deoxyguanosine is a click chemistry reagent containing an alkyne group. 6-O-Propynyl-2'-deoxyguanosine can be used for the research of various biochemical .
    6-O-Propynyl-2'-deoxyguanosine
  • HY-140924
    Dde Biotin-PEG4-alkyne

    		PROTAC Linkers Cancer
    Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Dde Biotin-PEG4-alkyne
  • HY-145472
    Sphingosine (d18:1) alkyne

    		Biochemical Assay Reagents Cancer
    Sphingosine (d18:1) alkyne (compound 2b) is an alkyne-labeled Sphingosine (d18:1) that can be used in click chemistry reactions .
    Sphingosine (d18:1) alkyne
  • HY-113803
    4-Hydroxynonenal alkyne

    4-HNE alkyne

    		 Biochemical Assay Reagents Cancer
    4-Hydroxynonenal alkyne (4-HNE alkyne) is a click chemical reagent containing alkynes. 4-Hydroxynonenal alkyne induces heme oxygenase and cell apoptosis in colon cancer (RKO) cells .
    4-Hydroxynonenal alkyne
  • HY-120317
    CPTH2-Alkyne

    		Histone Acetyltransferase Others
    CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .
    CPTH2-Alkyne
  • HY-151790
    Alkyne-SS-COOH

    		ADC Linker Others
    Alkyne-SS-COOH is a click chemistry reagent containing an alkyne group. Alkyne-SS-COOH can be used for the research of various biochemical .
    Alkyne-SS-COOH
  • HY-D2113
    TAMRA-PEG3-Alkyne

    		Fluorescent Dye Others
    TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    TAMRA-PEG3-Alkyne
  • HY-140925
    Diazo Biotin-PEG3-alkyne

    		PROTAC Linkers Cancer
    Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Diazo Biotin-PEG3-alkyne
  • HY-133430
    DBCO-PEG4-alkyne

    		ADC Linker Cancer
    DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DBCO-PEG4-alkyne
  • HY-W458035
    Desamino lenalidomide-alkynes

    		Ligands for E3 Ligase Cancer
    Desamino lenalidomide-alkynes is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-alkynes can be linked to a target protein ligand via a linker to form a PROTAC.
    Desamino lenalidomide-alkynes
  • HY-151643
    beta-Glc-TEG-Alkyne

    		ADC Linker Others
    beta-Glc-TEG-Alkyne is a click chemistry reagent containing an alkynes group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical .
    beta-Glc-TEG-Alkyne
  • HY-151728
    Trisulfo-Cy3-Alkyne

    		Fluorescent Dye Others
    Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only . Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Trisulfo-Cy3-Alkyne
  • HY-151794
    DACN(Ms) hydrochloride

    		ADC Linker Others
    DACN(Ms) hydrochloride (compound 1ba) is a click chemistry reagent containing cyclononyne alkyne. DCN(Ms) hydrochloride has high thermal stability, chemical stability, water solubility, and high reactivity for cycloaddition reactions .
    DACN(Ms) hydrochloride
  • HY-151684
    Boc-Ser(O-propargyl)-OH

    		ADC Linker Others
    Boc-Ser(O-propargyl)-OH is a click chemistry reagent containing an alkynes group. Boc-Ser(O-propargyl)-OH can be used for the research of various biochemical .
    Boc-Ser(O-propargyl)-OH
  • HY-151795
    DACN(Tos) hydrochloride

    		ADC Linker Others
    DACN(Tos) hydrochloride is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions, such strain-promoted azide-alkyne cycloadditions (SPAAC) by using cycloalkynes. DACNs possesses high thermal and chemical stability along with comparable click reactivity. DACN(Tos) hydrochloride can be used for the research of molecular conjugation .
    DACN(Tos) hydrochloride
  • HY-135970
    Alkyne-PEG4-SS-PEG4-alkyne

    		ADC Linker Cancer
    Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-PEG4-SS-PEG4-alkyne
  • HY-133496
    Folate-PEG3-alkyne

    		PROTAC Linkers Cancer
    Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Folate-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Folate-PEG3-alkyne
  • HY-136046
    PTAD-PEG4-alkyne

    		ADC Linker Cancer
    PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    PTAD-PEG4-alkyne
  • HY-136075
    HyNic-PEG4-alkyne

    		ADC Linker Cancer
    HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    HyNic-PEG4-alkyne
  • HY-133437
    BCN-PEG4-alkyne

    		PROTAC Linkers Cancer
    BCN-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-alkyne is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    BCN-PEG4-alkyne
  • HY-151649
    Biotin-PEG(4)-SS-Alkyne

    		ADC Linker Others
    Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an alkyne group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .
    Biotin-PEG(4)-SS-Alkyne
  • HY-W051612
    DL-Propargylglycine hydrochloride

    		Amino Acid Derivatives Others
    DL-Propargylglycine hydrochloride is a Glycine (HY-Y0966) derivative. DL-Propargylglycine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine hydrochloride
  • HY-135639
    Alkyne-probe 1

    		Fluorescent Dye Others
    Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-probe 1
  • HY-N16015
    C16:0(Alkyne) L-carnitine

    		Biochemical Assay Reagents Others
    C16:0(Alkyne) L-carnitine is a acyl carnitine lipid. C16:0(Alkyne) L-carnitine is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst.
    C16:0(Alkyne) L-carnitine
  • HY-140130
    PC Biotin-PEG3-alkyne

    		ADC Linker Cancer
    PC Biotin-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    PC Biotin-PEG3-alkyne
  • HY-140131
    Biotin-PEG4-PC-PEG4-alkyne

    		PROTAC Linkers Cancer
    Biotin-PEG4-PC-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-PC-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG4-PC-PEG4-alkyne
  • HY-174473
    Thalidomide-NH-alkynes

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-NH-alkynes is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC HDAC degrader-2 (HY-174444) .
    Thalidomide-NH-alkynes
  • HY-W836955
    Ts-PEG3-O-C-alkynes-TBS

    		PROTAC Linkers Cancer
    Ts-PEG3-O-C-alkynes-TBS is a PROTAC linker that can be used in the synthesis of PROTACs.
    Ts-PEG3-O-C-alkynes-TBS
  • HY-151683A
    H-L-Ser(Propargyl)-OH hydrochloride

    		ADC Linker Others
    H-L-Ser(Propargyl)-OH hydrochloride is a click chemistry reagent containing an alkyne group .
    H-L-Ser(Propargyl)-OH hydrochloride
  • HY-151683
    H-L-Ser(Propargyl)-OH

    		ADC Linker Others
    H-L-Ser(Propargyl)-OH is a click chemistry reagent containing an alkyne group .
    H-L-Ser(Propargyl)-OH
  • HY-151665
    Alkyne-PEG2-iodide

    		ADC Linker Others
    Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.
    Alkyne-PEG2-iodide
  • HY-147206C
    Biotin-PEG3400-Alk

    		Fluorescent Dye Others
    Biotin-PEG3400-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG3400-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG3400-Alk
  • HY-147206A
    Biotin-PEG1000-Alk

    		Fluorescent Dye Others
    Biotin-PEG1000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG1000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG1000-Alk
  • HY-147206E
    Biotin-PEG10000-Alk

    		Fluorescent Dye Others
    Biotin-PEG10000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG10000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG10000-Alk
  • HY-147206B
    Biotin-PEG2000-Alk

    		Fluorescent Dye Others
    Biotin-PEG2000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG2000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG2000-Alk
  • HY-147206F
    Biotin-PEG20000-Alk

    		Fluorescent Dye Others
    Biotin-PEG20000-Alk is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG20000-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG20000-Alk

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