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Results for "

anthraquinone compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (3) AMPK (1) Antibiotic (2) AP-1 (1) Apoptosis (2) Autophagy (4) Bacterial (13) Biochemical Assay Reagents (1) Calcium Channel (2) Casein Kinase (3) CCR (1) CDK (1) COX (3) CXCR (1) Dipeptidyl Peptidase (1) Drug Derivative (2) Endogenous Metabolite (1) ERK (3) FGFR (1) Fluorescent Dye (2) Fungal (2) GCGR (1) Glycosidase (2) Influenza Virus (1) Isotope-Labeled Compounds (1) JNK (3) MMP (1) NF-κB (2) NO Synthase (1) NOD-like Receptor (NLR) (1) p38 MAPK (3) Parasite (1) Phosphatase (2) Pyroptosis (1) Reactive Oxygen Species (ROS) (3) Reference Standards (3) RIG-I-like receptor (RLR) (1) SARS-CoV (3) STAT (1) TNF Receptor (2) Topoisomerase (1) Tyrosinase (1) VEGFR (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (3) Infection (14) Inflammation/Immunology (11) Metabolic Disease (5) Neurological Disease (5)

By Targets:

11β-HSD (3)

AMPK (1)

Antibiotic (2)

AP-1 (1)

Apoptosis (2)

Autophagy (4)

Bacterial (13)

Biochemical Assay Reagents (1)

Calcium Channel (2)

Casein Kinase (3)

CCR (1)

CDK (1)

COX (3)

CXCR (1)

Dipeptidyl Peptidase (1)

Drug Derivative (2)

Endogenous Metabolite (1)

ERK (3)

FGFR (1)

Fluorescent Dye (2)

Fungal (2)

GCGR (1)

Glycosidase (2)

Influenza Virus (1)

Isotope-Labeled Compounds (1)

JNK (3)

MMP (1)

NF-κB (2)

NO Synthase (1)

NOD-like Receptor (NLR) (1)

p38 MAPK (3)

Parasite (1)

Phosphatase (2)

Pyroptosis (1)

Reactive Oxygen Species (ROS) (3)

Reference Standards (3)

RIG-I-like receptor (RLR) (1)

SARS-CoV (3)

STAT (1)

TNF Receptor (2)

Topoisomerase (1)

Tyrosinase (1)

VEGFR (1)

By Research Areas:

Cancer (11)

Cardiovascular Disease (3)

Infection (14)

Inflammation/Immunology (11)

Metabolic Disease (5)

Neurological Disease (5)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14393

Emodin Maximum Cited Publications 39 Publications Verification Frangula emodin	SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N0105

Rhein 15+ Cited Publications Rheic Acid; Rhubarb yellow; Monorhein	Autophagy Reactive Oxygen Species (ROS) Bacterial Apoptosis	Infection Inflammation/Immunology Cancer
Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects ^{[1] ^.}

HY-N0571

Purpurin 1 Publications Verification	Fungal Bacterial Antibiotic	Infection Neurological Disease
Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .

HY-120601

Alizarin Red S sodium 5+ Cited Publications ARS sodium	Fluorescent Dye	Others
Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm .

HY-N0261

Aurantio-obtusin 1 Publications Verification	TNF Receptor COX	Cardiovascular Disease Inflammation/Immunology
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-120601A

Alizarin Red S 5+ Cited Publications ARS	Fluorescent Dye	Others
Alizarin Red S (ARS) is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm .

HY-N5091

Physcion 8-O-β-D-glucopyranoside	Others	Inflammation/Immunology Cancer
Physcion 8-O-β-D-glucopyranosideis an anthraquinone compound isolated from Rumex japonicus Houtt. Physcion 8-O-β-D-glucopyranoside exerts anti-inflammatory and anti-cancer properties, can be for common malignancy cancer research .

HY-W031757

Anthraquinone-2-carboxylic acid	Influenza Virus Bacterial Dipeptidyl Peptidase COX NF-κB AP-1 RIG-I-like receptor (RLR) STAT	Infection Neurological Disease Inflammation/Immunology
Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities .\n

HY-W008764

Anthrarufin 9,10-Anthracenedione, 1,5-dihydroxy-	Drug Derivative	Others
Anthrarufin (9,10-Anthracenedione, 1,5-dihydroxy-_) is an anthraquinone compound that has an inhibitory effect on the activity of the uterine mucosa during pregnancy .

HY-N8022

Lucidin primeveroside Lucidin 3-O-β-primeveroside	Biochemical Assay Reagents	Cancer
Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts .

HY-164853

Kanglexin	Pyroptosis NOD-like Receptor (NLR) ERK FGFR AMPK	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Kanglexin is an orally active and novel anthraquinone compound. Kanglexin inhibits NLRP3 inflammatory body activation and cell pyroptosis, and has a cardioprotective effect. Kanglexin promotes angiogenesis through FGFR1/ERK signaling pathway and accelerates diabetic wound healing. In addition, Kanglexin has the effect of lipid-lowering and inhibiting the dedifferentiation of vascular smooth muscle cells, and can be used in the study of hyperlipidemia, fatty liver and atherosclerosis .

HY-14393R

Emodin (Standard) Maximum Cited Publications 39 Publications Verification Frangula emodin (Standard)	Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-134000

Emodic acid NSC624610	p38 MAPK NF-κB ERK JNK VEGFR MMP	Cancer
Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells .

HY-137990

Questin	Bacterial Parasite Phosphatase	Infection Cancer
Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer .

HY-126597

Chaetoglobosin C	Bacterial	Infection
Chaetoglobosin C (Compound 4) is a anthraquinone-chromone compound derived from the fungus Chaetomium globosum KMITL-N0802. Chaetoglobosin C has anti-tuberculosis activity .

HY-119739

Skyrin 1 Publications Verification	GCGR	Metabolic Disease Cancer
Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells .

HY-N0571R

Purpurin (Standard)	Reference Standards Fungal Bacterial Antibiotic	Infection Neurological Disease
Purpurin (Standard) is the analytical standard of Purpurin. This product is intended for research and analytical applications. Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .

HY-130049

Lucidin ω-ethyl ether	Bacterial	Infection
Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria .

HY-N0312

Rhein-8-glucoside calcium	Phosphatase Bacterial	Infection Metabolic Disease
Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC₅₀ of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects .

HY-N0261R

Aurantio-obtusin (Standard)	Reference Standards TNF Receptor COX	Cardiovascular Disease Inflammation/Immunology
Aurantio-obtusin (Standard) is the analytical standard of Aurantio-obtusin. This product is intended for research and analytical applications. Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy-and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N16529

1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone	Glycosidase	Metabolic Disease
1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone (Compound 2) is a anthraquinone aglycone found in Cassia obtusefolia. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can inhibit α-glucosidase with an IC₅₀ of 120.65 μg/mL. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can be used for the research of diabetes .

HY-14393S

Emodin-d4 Frangula emodin-d₄	Isotope-Labeled Compounds SARS-CoV Casein Kinase Autophagy 11β-HSD	Cancer
Emodin-d₄ is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N16377

1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione	Others	Cancer
1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione (Compound 2) is an anthraquinone analog. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione can be isolated from soil Actinomycete Streptomyces. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has potent cytotoxicity against HepG2, A875, BGC-823 and MCF-7 cells with IC₅₀s of 2.29, 4.90, 0.99 and 1.66 μg/mL, respectively. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has an antitumor activity .

HY-N10369

1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone	Others	Others
1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone is an anthraquinone compound isolated from the seeds of Cassia obtusifolia .

HY-N15488

Islandicin	Bacterial	Infection
Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity .

HY-N11894

1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside	Others	Others
1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside ( Compound 20) is a quinone compound that can be isolated from the roots and rhizomes of Madder .

HY-N9961

2-Hydroxyl emodin-1-methyl ether	Others	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N12006

6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone	Glycosidase	Others
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds .

HY-146497

Topoisomerase I inhibitor 7	Topoisomerase	Cancer
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .

HY-121174

Alaternin Catharticin	NO Synthase CDK Tyrosinase Reactive Oxygen Species (ROS)	Metabolic Disease
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-N11723

Catenarin Katenarin	CCR CXCR p38 MAPK JNK Calcium Channel	Infection Metabolic Disease Inflammation/Immunology
Catenarin, an anthraquinone compound, inhibits CCR5- and CXCR4-mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases (p38 and JNK) and their upstream kinases (MKK6 and MKK7), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice ^[1][2].

HY-N11242

Cascaroside C	Drug Derivative	Others
Cascaroside C is an anthraquinone compound. Cascaroside C can be isolated from the roots of Rheum emodi and Rhamnus purshianus DC .

HY-113740

Knoxiadin	Others	Others
Knoxiadin (Compound 4) is an anthraquinone found in the roots of Knoxia valerianoides .

HY-N12009

1-Desmethylobtusin	Others	Others
1-Desmethylobtusin is an anthraquinone compound can be isolated from Cassia obtusifolia L .

HY-N17589

Purpurin-1-methylether	Others	Others
Purpurin-1-methylether (Compound 7) is an anthraquinone found in Galium spurium var. echinospermon Hayek .

HY-W925920

9,16-Dioxo-10,12,14-octadecatrienoic acid	Others	Others
9,16-Dioxo-10,12,14-octadecatrienoic acid (Compound 6) is an anthraquinone compound found in the rhizomes of Osmunda japonica Thunb .

HY-N17842

2,5,8-Trihydroxy-1-methoxyanthraquinone	Others	Others
2,5,8-Trihydroxy-1-methoxyanthraquinone (Compound 1) is an anthraquinone found in the roots of Morinda officinalis .

HY-N17915

2-Methyl-3,5,6-trihydroxyanthraquinone	Others	Others
2-Methyl-3,5,6-trihydroxyanthraquinone (compound 6) is an anthraquinone found in cell suspension cultures of Morinda citrifolia .

HY-N19079

Rheum emodi extract	Others	Inflammation/Immunology
Rheum emodi extract has laxative, anti-inflammatory, and antioxidant properties. Its main active ingredients include anthraquinone compounds (such as emodin, chrysophanol, and aloe-emodin), flavonoids, and tannins.

HY-N18652

Senna extract	Bacterial	Infection Inflammation/Immunology
Senna extract contains anthraquinone compounds, such as sennosides A and B, which have laxative properties. Sennosides in senna extract can stimulate colon muscles, promote intestinal peristalsis, and relieve constipation.

HY-N18677

Rubia cordifolia extract	Bacterial	Infection Inflammation/Immunology
Rubia cordifolia extract, derived from the roots of the madder plant, is valued for its anti-inflammatory, antioxidant, antibacterial, and blood-purifying properties. Active ingredients in Rubia cordifolia extract include anthraquinone compounds (such as alizarin and alizarin red), flavonoids, and tannins.

HY-N19063

Cassia alata extract	Bacterial	Infection Inflammation/Immunology
Cassia alata extract contains anthraquinones (including hypericic acid), flavonoids, phenolic compounds, fatty acids, natural sterols, terpenoids, and saponins, among other bioactive compounds. Cassia alata extract possesses antifungal, antibacterial, and anti-inflammatory properties and can be used in research on skin diseases such as tinea, eczema, and fungal infections.

HY-N12229

Penipurdin A	Endogenous Metabolite Bacterial	Infection
Penipurdin A (Compound 1), an anthraquinone, is a microbial secondary metabolite. Penipurdin A can be isolated from the soil fungus Penicillium purpurogenum SC0070. Penipurdin A has no significant cytotoxicity against cancer cells, such as A549, HepG2 and Hela cells. Penipurdin A has antibacterial activity against Enterococcus faecalis and Staphylococcus aureus .

HY-118817

Evariquinone	Reactive Oxygen Species (ROS) Calcium Channel JNK ERK p38 MAPK Apoptosis	Neurological Disease
Evariquinone is an anthraquinone compound isolated from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. Evariquinone possesses direct antioxidant activity. It inhibits excessive phosphorylation of the JNK, ERK1/2 and p38 MAPK signaling pathways by suppressing ROS and Ca ²⁺, thereby reducing neuronal apoptosis. Evariquinone can be used to study glutamate excitotoxicity-related neurological disorders (such as Alzheimer's disease, Parkinson's disease, cerebral ischemia, etc.) .

Cat. No.	Product Name

HY-L243

Quinones Library	92 compounds
Quinone compounds are a significant class of natural products featuring a conjugated quinone structure, widely distributed in plants, fungi, and microorganisms. Based on their core structures, they can be primarily categorized into benzoquinones, naphthoquinones, phenanthrenequinones, and anthraquinones, among others. This structural diversity endows quinone compounds with a broad spectrum of pharmacological activities, making them key components in traditional Chinese medicine (such as rhubarb, Lithospermum erythrorhizon, and Salvia miltiorrhiza). Modern research has confirmed that their activities encompass anti-tumor, anti-inflammatory, antibacterial, antiviral, antiplatelet aggregation, and neuroprotective effects, among others, establishing them as an important source for drug development. MCE designs a unique collection of 92 quinones that all come from natural products. MCE Quinones Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Quinones Library

92 compounds

Quinone compounds are a significant class of natural products featuring a conjugated quinone structure, widely distributed in plants, fungi, and microorganisms. Based on their core structures, they can be primarily categorized into benzoquinones, naphthoquinones, phenanthrenequinones, and anthraquinones, among others. This structural diversity endows quinone compounds with a broad spectrum of pharmacological activities, making them key components in traditional Chinese medicine (such as rhubarb, Lithospermum erythrorhizon, and Salvia miltiorrhiza). Modern research has confirmed that their activities encompass anti-tumor, anti-inflammatory, antibacterial, antiviral, antiplatelet aggregation, and neuroprotective effects, among others, establishing them as an important source for drug development.

MCE designs a unique collection of 92 quinones that all come from natural products. MCE Quinones Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-14393

Emodin Maximum Cited Publications 39 Publications Verification Frangula emodin	Classification of Application Fields Polygonaceae Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Source Classification Cancer	SARS-CoV Casein Kinase Autophagy 11β-HSD
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-N0105

Rhein 15+ Cited Publications Rheic Acid; Rhubarb yellow; Monorhein	Infection Quinones Rheum palmatum L. Classification of Application Fields Anthraquinones Polygonaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Autophagy Reactive Oxygen Species (ROS) Bacterial Apoptosis
Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects ^{[1] ^.}

HY-N0571

Purpurin 1 Publications Verification	Quinones Anthraquinones Rubiaceae Phenols Polyphenols Plants Rubia cordifolia L. Source Classification	Fungal Bacterial Antibiotic
Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .

HY-N0261

Aurantio-obtusin 1 Publications Verification	Seeds of Cassia tora Linn. Cardiovascular Disease Classification of Application Fields Plants Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Inflammation/Immunology Disease Research Fields Source Classification	TNF Receptor COX
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N5091

Physcion 8-O-β-D-glucopyranoside	Quinones Monophenols other families Classification of Application Fields Anthraquinones Phenols Plants Disease Research Fields Inflammation/Immunology Source Classification	Others
Physcion 8-O-β-D-glucopyranosideis an anthraquinone compound isolated from Rumex japonicus Houtt. Physcion 8-O-β-D-glucopyranoside exerts anti-inflammatory and anti-cancer properties, can be for common malignancy cancer research .

HY-W031757

Anthraquinone-2-carboxylic acid	Quinones Structural Classification other families Classification of Application Fields Anthraquinones Acrostichum speciosum Willd. Plants Inflammation/Immunology Disease Research Fields	Influenza Virus Bacterial Dipeptidyl Peptidase COX NF-κB AP-1 RIG-I-like receptor (RLR) STAT
Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities .\n

HY-N8022

Lucidin primeveroside Lucidin 3-O-β-primeveroside	Quinones Monophenols Classification of Application Fields Anthraquinones Rubiaceae Phenols Plants Disease Research Fields Rubia cordifolia L. Source Classification Cancer	Biochemical Assay Reagents
Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts .

HY-14393R

Emodin (Standard) Maximum Cited Publications 39 Publications Verification Frangula emodin (Standard)	Quinones Rheum palmatum L. Classification of Application Fields Polygonaceae Phenols Plants Disease Research Fields Source Classification Cancer	Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD
Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

HY-134000

Emodic acid NSC624610	Quinones Human Gut Microbiota Metabolites Microorganisms Leguminosae Cercis chinensis Bunge Anthraquinones Plants Endogenous metabolite Source Classification	p38 MAPK NF-κB ERK JNK VEGFR MMP
Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells .

HY-137990

Questin	Classification of Application Fields Marine natural products Endogenous metabolite Infection Quinones Human Gut Microbiota Metabolites Microorganisms Anthraquinones Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	Bacterial Parasite Phosphatase
Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays antiprotozoal activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer .

HY-126597

Chaetoglobosin C	Alkaloids Microorganisms Indole Alkaloids Source Classification	Bacterial
Chaetoglobosin C (Compound 4) is a anthraquinone-chromone compound derived from the fungus Chaetomium globosum KMITL-N0802. Chaetoglobosin C has anti-tuberculosis activity .

HY-119739

Skyrin 1 Publications Verification	Ventilago leiocarpa Benth. Quinones Anthraquinones Plants Rhamnaceae Source Classification	GCGR
Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells .

HY-N0571R

Purpurin (Standard)	Quinones Structural Classification Anthraquinones Rubiaceae Phenols Polyphenols Plants Rubia cordifolia L. Source Classification	Reference Standards Fungal Bacterial Antibiotic
Purpurin (Standard) is the analytical standard of Purpurin. This product is intended for research and analytical applications. Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .

HY-130049

Lucidin ω-ethyl ether	Quinones Anthraquinones Rubiaceae Plants Prismatomeris filamentosa Craib Source Classification	Bacterial
Lucidin ω-ethyl ether (compound 17) is an anthraquinone metabolite isolated from the root part of Prismatomeris filamentosa with some antibacterial activity against Gram-positive and Gram-negative bacteria .

HY-N0312

Rhein-8-glucoside calcium	Quinones Monophenols Classification of Application Fields Rheum palmatum L. Anthraquinones Polygonaceae Phenols Metabolic Disease Plants Disease Research Fields Source Classification	Phosphatase Bacterial
Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC₅₀ of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects .

HY-N0261R

Aurantio-obtusin (Standard)	Seeds of Cassia tora Linn. Quinones Structural Classification other families Leguminosae Anthraquinones Phenols Polyphenols Plants Source Classification	Reference Standards TNF Receptor COX
Aurantio-obtusin (Standard) is the analytical standard of Aurantio-obtusin. This product is intended for research and analytical applications. Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy-and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N16529

1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone	Structural Classification Xanthones Securidaca inappendiculata Hassk. Polygalaceae Phenols Plants Source Classification	Glycosidase
1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone (Compound 2) is a anthraquinone aglycone found in Cassia obtusefolia. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can inhibit α-glucosidase with an IC₅₀ of 120.65 μg/mL. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can be used for the research of diabetes .

HY-N16377

1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione	Quinones Microorganisms Anthraquinones Source Classification	Others
1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione (Compound 2) is an anthraquinone analog. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione can be isolated from soil Actinomycete Streptomyces. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has potent cytotoxicity against HepG2, A875, BGC-823 and MCF-7 cells with IC₅₀s of 2.29, 4.90, 0.99 and 1.66 μg/mL, respectively. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has an antitumor activity .

HY-N10369

1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone	Quinones Classification of Application Fields Anthraquinones Other Diseases Phenols Polyphenols Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Disease Research Fields Source Classification	Others
1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone is an anthraquinone compound isolated from the seeds of Cassia obtusifolia .

HY-N15488

Islandicin	Quinones Microorganisms Anthraquinones Source Classification	Bacterial
Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity .

HY-N11894

1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside	Quinones Rubia podantha Anthraquinones Rubiaceae Plants Source Classification	Others
1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside ( Compound 20) is a quinone compound that can be isolated from the roots and rhizomes of Madder .

HY-N9961

2-Hydroxyl emodin-1-methyl ether	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N12006

6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Glycosidase
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds .

HY-121174

Alaternin Catharticin	Flavonoids Plants Rhamnaceae Rhamnus saxatilis X. H. Song Source Classification	NO Synthase CDK Tyrosinase Reactive Oxygen Species (ROS)
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO₄/H₂O₂) with an IC₅₀ value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC₅₀ value of 4.02 μM .

HY-N11723

Catenarin Katenarin	Quinones Microorganisms Anthraquinones Source Classification	CCR CXCR p38 MAPK JNK Calcium Channel
Catenarin, an anthraquinone compound, inhibits CCR5- and CXCR4-mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases (p38 and JNK) and their upstream kinases (MKK6 and MKK7), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice ^[1][2].

HY-N11242

Cascaroside C	Quinones Structural Classification Rheum australe D. Don Anthraquinones Polygonaceae Plants Source Classification	Drug Derivative
Cascaroside C is an anthraquinone compound. Cascaroside C can be isolated from the roots of Rheum emodi and Rhamnus purshianus DC .

HY-113740

Knoxiadin	Quinones Structural Classification Anthraquinones Rubiaceae Knoxia valerianoides Thorel ex Pitard Plants Source Classification	Others
Knoxiadin (Compound 4) is an anthraquinone found in the roots of Knoxia valerianoides .

HY-N12009

1-Desmethylobtusin	Quinones Anthraquinones Caesalpiniaceae Cassia obtusifolia (L.) H. S. Irwin & Barneby Plants Source Classification	Others
1-Desmethylobtusin is an anthraquinone compound can be isolated from Cassia obtusifolia L .

HY-N17589

Purpurin-1-methylether	Quinones Structural Classification Galium aparine L. Anthraquinones Rubiaceae Plants Source Classification	Others
Purpurin-1-methylether (Compound 7) is an anthraquinone found in Galium spurium var. echinospermon Hayek .

HY-W925920

9,16-Dioxo-10,12,14-octadecatrienoic acid	Osmundaceae Structural Classification Ketones, Aldehydes, Acids Labiatae Elaeagnaceae Elaeagnus lanceolata Warb. Osmunda japonica Plants Lepidagathis cuspidata Nees Source Classification	Others
9,16-Dioxo-10,12,14-octadecatrienoic acid (Compound 6) is an anthraquinone compound found in the rhizomes of Osmunda japonica Thunb .

HY-N17842

2,5,8-Trihydroxy-1-methoxyanthraquinone	Quinones Structural Classification Anthraquinones Rubiaceae Plants Morinda officinalis How Source Classification	Others
2,5,8-Trihydroxy-1-methoxyanthraquinone (Compound 1) is an anthraquinone found in the roots of Morinda officinalis .

HY-N17915

2-Methyl-3,5,6-trihydroxyanthraquinone	Quinones Structural Classification Anthraquinones Morinda citrifolia Linn. Rubiaceae Plants Source Classification	Others
2-Methyl-3,5,6-trihydroxyanthraquinone (compound 6) is an anthraquinone found in cell suspension cultures of Morinda citrifolia .

HY-N19079

Rheum emodi extract	Structural Classification Extract	Others
Rheum emodi extract has laxative, anti-inflammatory, and antioxidant properties. Its main active ingredients include anthraquinone compounds (such as emodin, chrysophanol, and aloe-emodin), flavonoids, and tannins.

HY-N18652

Senna extract	Structural Classification Extract	Bacterial
Senna extract contains anthraquinone compounds, such as sennosides A and B, which have laxative properties. Sennosides in senna extract can stimulate colon muscles, promote intestinal peristalsis, and relieve constipation.

HY-N18677

Rubia cordifolia extract	Structural Classification Extract	Bacterial
Rubia cordifolia extract, derived from the roots of the madder plant, is valued for its anti-inflammatory, antioxidant, antibacterial, and blood-purifying properties. Active ingredients in Rubia cordifolia extract include anthraquinone compounds (such as alizarin and alizarin red), flavonoids, and tannins.

HY-N19063

Cassia alata extract	Structural Classification Extract	Bacterial
Cassia alata extract contains anthraquinones (including hypericic acid), flavonoids, phenolic compounds, fatty acids, natural sterols, terpenoids, and saponins, among other bioactive compounds. Cassia alata extract possesses antifungal, antibacterial, and anti-inflammatory properties and can be used in research on skin diseases such as tinea, eczema, and fungal infections.

HY-N12229

Penipurdin A	Quinones Microorganisms Anthraquinones Source Classification	Endogenous Metabolite Bacterial
Penipurdin A (Compound 1), an anthraquinone, is a microbial secondary metabolite. Penipurdin A can be isolated from the soil fungus Penicillium purpurogenum SC0070. Penipurdin A has no significant cytotoxicity against cancer cells, such as A549, HepG2 and Hela cells. Penipurdin A has antibacterial activity against Enterococcus faecalis and Staphylococcus aureus .

HY-118817

Evariquinone	Quinones Structural Classification Microorganisms Anthraquinones Source Classification	Reactive Oxygen Species (ROS) Calcium Channel JNK ERK p38 MAPK Apoptosis
Evariquinone is an anthraquinone compound isolated from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. Evariquinone possesses direct antioxidant activity. It inhibits excessive phosphorylation of the JNK, ERK1/2 and p38 MAPK signaling pathways by suppressing ROS and Ca ²⁺, thereby reducing neuronal apoptosis. Evariquinone can be used to study glutamate excitotoxicity-related neurological disorders (such as Alzheimer's disease, Parkinson's disease, cerebral ischemia, etc.) .

Cat. No.	Product Name	Chemical Structure

HY-14393S

Emodin-d4

Emodin-d₄ is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .

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