117-78-2
Chemical Structure
Anthraquinone-2-carboxylic acid
- CAS No.: 117-78-2
- Formula:C15H8O4
- Molecular Weight:252.22
IUPAC Name: 9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
InChIKey: ASDLSKCKYGVMAI-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC=C1)C(C=C3C(O)=O)=C(C=C3)C2=O
Biological Activity:
Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities[1][2][3].\n
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Anthraquinone-2-carboxylic acid | 98.0% | Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities.\n |
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Anthraquinone-2-carboxylic acid (Standard) | ≥98% | Anthraquinone-2-carboxylic acid (Standard) is the analytical standard of Anthraquinone-2-carboxylic acid (HY-W031757). This product is intended for research and analytical applications. Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities.\n |
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Similarity Score 0.85
HY-N7502R2-(Hydroxymethyl)anthraquinone (Standard) -
Similarity Score 0.83
HY-W2966799,10-Dioxo-9,10-dihydro-anthracene-2,6-dicarboxylic acid -
Similarity Score 0.82
HY-N1739Tectoquinone -
Similarity Score 0.81
HY-W012352R2-Hydroxyanthraquinone (Standard) -
Similarity Score 0.80
HY-W0132639,10-dioxo-9,10-dihydroanthracene-2,3-dicarboxylic acid -
Similarity Score 0.77
HY-N0354Anthraquinone -
Similarity Score 0.77
HY-N87892-Hydroxymethyl-3-hydroxyanthraquinone -
Similarity Score 0.75
HY-W4564819,10-Dioxo-9,10-dihydroanthracene-1,4-dicarboxylic acid -
Similarity Score 0.75
HY-N71602-Hydroxy-3-methylanthraquinone -
Explore the MedChemAI to find more analogs
References
- [1]. Park JG, et al. Anti-Inflammatory and Antinociceptive Activities of Anthraquinone-2-Carboxylic Acid. Mediators Inflamm. 2016;2016:1903849. [Content Brief]
- [2]. Ren S, et al. Anthraquinone-2-Carboxylic Acid Is a Potential Antiviral Candidate Against Influenza Viruses In Vitro and In Vivo. Viruses. 2025;17(5):628. Published 2025 Apr 27. [Content Brief]
- [3]. Srivastava P, et al. Synergistic action between copper oxide (CuO) nanoparticles and anthraquinone-2-carboxylic acid (AQ) against Staphylococcus aureus[J]. Journal of Composites Science, 2023, 7(4): 135.
