117-78-2
Chemical Structure
Anthraquinone-2-carboxylic acid
- CAS No.: 117-78-2
- Formula:C15H8O4
- Molecular Weight:252.22
IUPAC Name: 9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
InChIKey: ASDLSKCKYGVMAI-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC=C1)C(C=C3C(O)=O)=C(C=C3)C2=O
Biological Activity:
Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities[1][2][3].\n
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Anthraquinone-2-carboxylic acid | 98.0% | Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities.\n |
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Anthraquinone-2-carboxylic acid (Standard) | ≥98% | Anthraquinone-2-carboxylic acid (Standard) is the analytical standard of Anthraquinone-2-carboxylic acid (HY-W031757). This product is intended for research and analytical applications. Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities.\n |
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Anthraquinone | 98.84% | Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis. | ||||||||||||||||||||
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1-Hydroxy-2-methylanthraquinone | 1-Hydroxy-2-methylanthraquinone exhibits antimicrobial, antioxidant, pesticidal, and anti-inflammatory activities. | |||||||||||||||||||||
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Tectoquinone | 98.24% | Tectoquinone (2-Methylanthraquinone) is an inhibitor for SARS CoV-2 major protease (SARS CoV-2 Mpro). Tectoquinone exhibits anti-termite and antiviral activities. | ||||||||||||||||||||
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2-Hydroxy-3-methylanthraquinone | 98.67% | 2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells. | ||||||||||||||||||||
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2-(Hydroxymethyl)anthraquinone (Standard) | ≥98% | 2-(Hydroxymethyl)anthraquinone is used as a photoremovable protecting group (PRPG) to chemically cage sex pheromone (e.g. (Z)-11-hexadecen-1-ol (sex pheromone of Chilo infuscatellussnellen)). | ||||||||||||||||||||
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2-Hydroxymethyl-3-hydroxyanthraquinone | 2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity. | |||||||||||||||||||||
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2-Hydroxyanthraquinone (Standard) | ≥98% | 2-Hydroxyanthraquinone (Standard) is the analytical standard of 2-Hydroxyanthraquinone (HY-W012352). This product is intended for research and analytical applications. 2-Hydroxyanthraquinone is a product generated by the photochemical oxidation of Anthracene (ANT) (HY-Y0299). 2-Hydroxyanthraquinone induces ferroptosis in cardiomyocytes by depleting GSH and inhibiting GPX4, leading to cardiac developmental malformations. 2-Hydroxyanthraquinone causes damage to the cerebrovascular system and blood-brain barrier in zebrafish by downregulating the Wnt/β-catenin signaling pathway, as well as inducing inflammation and neuronal apoptosis. 2-Hydroxyanthraquinone can be used in studies related to cerebrovascular diseases and cardiotoxicity. | ||||||||||||||||||||
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9,10-dioxo-9,10-dihydroanthracene-2,3-dicarboxylic acid | ||||||||||||||||||||||
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9,10-Dioxo-9,10-dihydro-anthracene-2,6-dicarboxylic acid | 9,10-Dioxo-9,10-dihydro-anthracene-2,6-dicarboxylic acid (Anthraquinone-2,6-dicarboxylic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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9,10-Dioxo-9,10-dihydroanthracene-1,4-dicarboxylic acid | 9,10-Dioxo-9,10-dihydroanthracene-1,4-dicarboxylic acid (9,10-Dioxo-9,10-dihydro-1,4-anthracenedicarboxylic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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References
- [1]. Park JG, et al. Anti-Inflammatory and Antinociceptive Activities of Anthraquinone-2-Carboxylic Acid. Mediators Inflamm. 2016;2016:1903849. [Content Brief]
- [2]. Ren S, et al. Anthraquinone-2-Carboxylic Acid Is a Potential Antiviral Candidate Against Influenza Viruses In Vitro and In Vivo. Viruses. 2025;17(5):628. Published 2025 Apr 27. [Content Brief]
- [3]. Srivastava P, et al. Synergistic action between copper oxide (CuO) nanoparticles and anthraquinone-2-carboxylic acid (AQ) against Staphylococcus aureus[J]. Journal of Composites Science, 2023, 7(4): 135.