478-45-5
Chemical Structure
Emodic acid
Synonym(s): NSC624610
- CAS. Nr.: 478-45-5
- Formula:C15H8O7
- Molecular Weight:300.22
IUPAC Name: 4,5,7-trihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
InChIKey: ZJXVNNSMRGTDBI-UHFFFAOYSA-N
SMILES: OC1=CC(O)=CC(C(C2=C3C(O)=CC(C(O)=O)=C2)=O)=C1C3=O
Biological Activity: Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells[1].
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Emodic acid | 98.00% | Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1β and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells. | ||||||||||||||||||||
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