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bases

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61

Inhibitors & Agonists

1

Screening Libraries

7

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8

Biochemical Assay Reagents

4

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13

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5

Isotope-Labeled Compounds

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1300
    LysoTracker Red
    10+ Cited Publications

    LysoTracker Red DND-99

    		 Biochemical Assay Reagents Fluorescent Dye Others
    LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
    LysoTracker Red
  • HY-I0626
    Cytosine
    3 Publications Verification

    		 Endogenous Metabolite Cancer
    Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research .
    Cytosine
  • HY-150743
    ODN 2395

    		Toll-like Receptor (TLR) Infection Inflammation/Immunology
    ODN 2395 is a C class oligodeoxynucleotide and can be used as vaccine adjuvant. ODN 2395 is also a TLR9 agonist. ODN 2395 can be used in the research of immunological vaccines. Sequence: 5'-tcgtcgttttcggcgc:gcgccg-3' (Note: The bases are phosphorothioate; ODN 2395 contains the partial palindromic sequence cggcgc:gcgccg) .
    ODN 2395
  • HY-DY1040
    LysoTracker Red (solution)

    		Fluorescent Dye Biochemical Assay Reagents Others
    LysoTracker Red (solution) is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
    Solvent and concentration: DMSO: 1 mM
    LysoTracker Red (solution)
  • HY-W010450
    Thymine
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease Cancer
    Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a Km value of 2.2 μM, Ki of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg .
    Thymine
  • HY-W012642
    2-Aminopurine

    		DNA Stain Others
    2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics .
    2-Aminopurine
  • HY-113110
    Cysteinylglycine

    L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH

    		 Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Cardiovascular Disease Cancer
    Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
    Cysteinylglycine
  • HY-34431
    Purine

    7H-Imidazo(4,5-d)pyrimidine

    		 Endogenous Metabolite PARP Neurological Disease Metabolic Disease Cancer
    Purine is an endogenous metabolite. Purine bases are the building blocks of the nucleic acids. Purine inhibits the activation of PARP. Purine protects against oxidant-induced cell injury. Purine can be used in the research of cancer and nervous system diseases .
    Purine
  • HY-W018326
    Temozolomide acid

    		DNA/RNA Synthesis Cancer
    Temozolomide acid is a carboxylic acid derivative of Temozolomide (HY-17364) with anticancer activity. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid is promising for research of glioblastoma and brain cancer .
    Temozolomide acid
  • HY-D1296
    Green DND-26
    2 Publications Verification

    		 Fluorescent Dye Others
    Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .
    Green DND-26
  • HY-113306
    1-Methyladenine

    		Endogenous Metabolite Others
    1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T-A base pairs in double-stranded DNA into non-disruptive T (anti)m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, 1-Methyladenine transforms into cytotoxic DNA damage and blocks the replication process .
    1-Methyladenine
  • HY-Y0912
    HBTU

    N-HBTU

    		 Biochemical Assay Reagents Inflammation/Immunology
    HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
    HBTU
  • HY-W008469
    2-Fluoroadenine

    		DNA/RNA Synthesis Cancer
    2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer .
    2-Fluoroadenine
  • HY-N11684
    Cocoa butter

    		Biochemical Assay Reagents Others
    Cocoa butter can be used as an excipient, such as lubricants, suppository bases. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Cocoa butter
  • HY-150014
    AMT-NHS

    		Others Others
    AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
    AMT-NHS
  • HY-W007479
    2,3-Dihydroxybenzaldehyde

    		Biochemical Assay Reagents Others
    2,3-Dihydroxybenzaldehyde can be used to synthesize copper(II) complexes of Schiff bases. 2,3-Dihydroxybenzaldehyde can also be used in the synthesis of 2-ethoxy-3-hydroxy-4-nitrobenzoic acid .
    2,3-Dihydroxybenzaldehyde
  • HY-145657
    Benzoquinoquinoxaline

    BQQ

    		 Biochemical Assay Reagents Others
    Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure .
    Benzoquinoquinoxaline
  • HY-77785
    2-Amino-5-chlorobenzophenone
    1 Publications Verification

    5-Chloro-2-aminobenzophenone

    		 Drug Intermediate Infection Neurological Disease
    2-Amino-5-chlorobenzophenone (5-Chloro-2-aminobenzophenone) is a chemical intermediate. Derivatives of 2-Amino-5-chlorobenzophenone serve as skeletal muscle relaxants. 2-Amino-5-chlorobenzophenone acts as a starting material for the synthesis of anti-biofilm 2-amino-5-chlorobenzophenone Schiff bases. 2-Amino-5-chlorobenzophenone is applicable to research related to bacterial infections .\n
    2-Amino-5-chlorobenzophenone
  • HY-W008048
    2',3'-O-Isopropylideneadenosine

    		Nucleoside Antimetabolite/Analog Others
    2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
    2',3'-O-Isopropylideneadenosine
  • HY-115736A
    Xanthosine-5'-Triphosphate trisodium solution (100 mM)

    5'-XTP trisodium

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphatase Others
    Xanthosine-5'-Triphosphate (5'-XTP) trisodium, a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate trisodium is a substrate of inosine triphosphate pyrophosphatase (ITPase) .
    Xanthosine-5'-Triphosphate trisodium solution (100 mM)
  • HY-I0626R
    Cytosine (Standard)

    		Reference Standards Endogenous Metabolite Others
    Cytosine (Standard) is the analytical standard of Cytosine. This product is intended for research and analytical applications. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging .
    Cytosine (Standard)
  • HY-N10706A
    3-Keto sphinganine (d18:0) hydrochloride

    		Endogenous Metabolite Cardiovascular Disease
    3-Keto sphinganine (d18:0) hydrochloride serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) hydrochloride can be used in studies related to thrombocytopenia, anemia .
    3-Keto sphinganine (d18:0) hydrochloride
  • HY-W013677
    4-Fluorobenzoic acid

    		Drug Intermediate Infection
    4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity .
    4-Fluorobenzoic acid
  • HY-I0626S2
    Cytosine-d2

    		Endogenous Metabolite Others
    Cytosine-d2 is the deuterium labeled Cytosine . Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging .
    Cytosine-d2
  • HY-W002593
    2-Acetyl-6-bromopyridine

    		Biochemical Assay Reagents Others
    2-Acetyl-6-bromopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Acetyl-6-bromopyridine can be used to synthesize Schiff bases containing cycloalkyl substituents .
    2-Acetyl-6-bromopyridine
  • HY-W541025
    Deoxyribonucleic acid

    		Biochemical Assay Reagents Others
    Deoxyribonucleic acid is a polymer formed by two polynucleotide chains twisted around each other to form a double-helix structure. Deoxyribonucleic acid exists in all dividing cells and is a fundamental component of chromosomes .
    Deoxyribonucleic acid
  • HY-115736
    Xanthosine-5'-Triphosphate

    5'-XTP

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphatase Others
    Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate is a substrate of inosine triphosphate pyrophosphatase (ITPase) .
    Xanthosine-5'-Triphosphate
  • HY-I0626S1
    Cytosine-13C,15N2

    		Endogenous Metabolite Others
    Cytosine- 13C, 15N2 is the 13C and 15N labeled Cytosine . Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging .
    Cytosine-13C,15N2
  • HY-W001974
    7-Nitroindole

    		DNA/RNA Synthesis Bacterial Others
    7-Nitroindole is a cleavable base analog and Antibacterial agent. 7-Nitroindole inhibits the growth of Lactobacillus arabinosus. 7-Nitroindole is used in studies of light-controlled DNA cleavage and Lactobacillus arabinosus infection .
    7-Nitroindole
  • HY-W046786
    Benzylisatin

    		Biochemical Assay Reagents Others
    Benzylisatin is a biologically potent derivative of isatin. Benzylisatin is used to prepare many new biologically potent Schiff bases and complexes suitable for medicinal purposes .
    Benzylisatin
  • HY-W142631
    4-(Phenylazo)diphenylamine

    		Fluorescent Dye Cancer
    4-(Phenylazo)diphenylamine is an excellent colorimetric indicator for the accurate determination of the concentration for a variety of strong bases, Lewis acids, and hydride reducing agents .
    4-(Phenylazo)diphenylamine
  • HY-124455
    Lunine

    		Endogenous Metabolite Others
    Lunine is an alkaloid isolated from Lunasia quercifolia. Lunine is resistant to acids, bases, oxidants and reducing agents .
    Lunine
  • HY-I0626S
    Cytosine-13C2,15N3

    		Endogenous Metabolite Others
    Cytosine- 13C2, 15N3 is the 13C-labeled and 15N-labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging .
    Cytosine-13C2,15N3
  • HY-134529
    D-Ribofuranose1-dihydrogenphosphate

    Ribose 1-phosphate

    		 Endogenous Metabolite Others
    D-Ribofuranose 1-dihydrogenphosphate (Ribose 1-phosphate) dicyclohexanamine is a pentose phosphate and serves as a key intermediate metabolite in the salvage synthesis pathway of purine and pyrimidine nucleotides. In nucleotide salvage synthesis, D-Ribofuranose 1-dihydrogenphosphate dicyclohexanamine directly "transfers" the ribosyl group from purine nucleosides to pyrimidine bases, acting as a hub molecule linking nucleoside/base metabolism with pentose phosphate metabolism .
    D-Ribofuranose1-dihydrogenphosphate
  • HY-P2724A
    Purine nucleoside phosphorylase, Bacillus sp.

    PNP, Bacillus sp.

    		 Endogenous Metabolite Metabolic Disease
    Purine nucleoside phosphorylase, Bacillus sp. is a key enzyme in purine metabolism, involved in the purine salvage pathway. A deficiency in Purine nucleoside phosphorylase, Bacillus sp. can lead to impaired T-cell function. In the presence of inorganic phosphate as a second substrate, Purine nucleoside phosphorylase, Bacillus sp. catalyzes the cleavage of the glycosidic bond of ribonucleosides and deoxyribonucleosides, producing purine bases and ribose (or deoxyribose)-1-phosphate. Purine nucleoside phosphorylase, Bacillus sp. can be used for the determination of inorganic phosphate .
    Purine nucleoside phosphorylase, Bacillus sp.
  • HY-113110R
    Cysteinylglycine (Standard)

    L-Cysteinylglycine (Standard); Cys-Gly (Standard); H-Cys-Gly-OH (Standard)

    		 Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) DNA/RNA Synthesis Cardiovascular Disease Cancer
    Cysteinylglycine (Standard) is the analytical standard of Cysteinylglycine. This product is intended for research and analytical applications. Cysteinylglycine is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
    Cysteinylglycine (Standard)
  • HY-W008469R
    2-Fluoroadenine (Standard)

    		Reference Standards DNA/RNA Synthesis Cancer
    2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer .
    2-Fluoroadenine (Standard)
  • HY-112501
    Codon readthrough inducer 1

    		DNA/RNA Synthesis Others
    Codon readthrough inducer 1, containing pyrimidine bases, shows good readthrough activity.
    Codon readthrough inducer 1
  • HY-N1567
    Pterolactam

    		Fungal Infection
    Pterolactam can be isolated from Chrysanthemum coronarium L. Pterolactam derivates serval analogues that Mannich bases of amide with antifungal activities and cytotoxicity .
    Pterolactam
  • HY-E70023
    Sphingolipid ceramide N-deacylase (SCDase)

    		Endogenous Metabolite Metabolic Disease
    Sphingolipid ceramide N-deacylase (SCDase) cleaves the N-acyl linkage between fatty acids and sphingosine bases in various glycosphingolipids. Sphingolipid ceramide N-deacylase catalyzes glycosphingolipids to lysoglycosphingolipids .
    Sphingolipid ceramide N-deacylase (SCDase)
  • HY-D1757
    Lucifer yellow ethylenediamine

    LYen; PAsp- LY

    		 Fluorescent Dye Others
    Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
    Lucifer yellow ethylenediamine
  • HY-177371
    CEBPA-51 saRNA

    		Nucleoside Antimetabolite/Analog Cancer
    CEBPA-51 saRNA, a double-stranded RNA oligo duplex to specifically upregulate the transcription of the CEBPA gene. CEBPA-51 saRNA contains multiple 2′-O-methyl modified bases to prevent nonspecific immunostimulatory activity .
    CEBPA-51 saRNA
  • HY-E70585
    T4 Phage β-glucosyltransferase

    		DNA/RNA Synthesis Others
    T4 Phage β-glucosyltransferase is a DNA-modifying enzyme encoded by bacteriophage T4. T4 Phage β-glucosyltransferase transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA .
    T4 Phage β-glucosyltransferase
  • HY-W013677S
    4-Fluorobenzoic acid-13C6

    		Isotope-Labeled Compounds Drug Intermediate Infection
    4-Fluorobenzoic acid- 13C6 is the 13C6 labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.
    4-Fluorobenzoic acid-13C6
  • HY-179668A
    10x TE buffer, pH 8.0

    		Biochemical Assay Reagents Others
    10x TE buffer, pH 8.0 is weakly alkaline and protects the bases of DNA. DNA is relatively stable in TE and is not easily damaged in terms of integrity or prone to ring opening and breakage. 1x TE buffer, pH 8.0 composition concentration: 100 mM Tris-HCl, 10 mM EDTA, pH 8.0.
    10x TE buffer, pH 8.0
  • HY-161071
    Antioxidant/anticancer agent 1

    		Fungal Infection Cancer
    Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1 .
    Antioxidant/anticancer agent 1
  • HY-N0157C
    Orotic acid potassium
    3 Publications Verification

    6-Carboxyuracil potassium; Vitamin B13 potassium

    		 Endogenous Metabolite DNA/RNA Synthesis Metabolic Disease
    Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats .
    Orotic acid potassium
  • HY-160048
    PEG40K unconjugated/naked AX102 sodium

    		PDGFR Cancer
    PEG40K unconjugated/naked AX102 sodium is AX102 without PEG40K conjugation. AX102 is a DNA oligonucleotide aptamer for platelet-derived growth factor PDGF-B. AX102 is 34 bases in length, selectively binds platelet-derived growth factor B (PDGF-B), and causes tumor vessel regression .
    PEG40K unconjugated/naked AX102 sodium
  • HY-115736B
    Xanthosine-5'-triphosphate lithium

    5'-XTP lithium

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphatase Others
    Xanthosine-5'-Triphosphate (5'-XTP) lithium, a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate lithium is a substrate of inosine triphosphate pyrophosphatase (ITPase) .
    Xanthosine-5'-triphosphate lithium
  • HY-W574398
    Fmoc-Aeg-OH

    		Biochemical Assay Reagents Others
    Fmoc-Aeg-OH is a peptide nucleic acid (PNA) backbone intermediate and an Fmoc-protected carboxylic acid. Fmoc-Aeg-OH can be coupled with base acetic acids to synthesize Fmoc-protected PNA monomers, including those with modified bases .
    Fmoc-Aeg-OH

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