362-75-4
Chemical Structure
2',3'-O-Isopropylideneadenosine
- CAS No.: 362-75-4
- Formula:C13H17N5O4
- Molecular Weight:307.31
IUPAC Name: ((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol
InChIKey: LCCLUOXEZAHUNS-WOUKDFQISA-N
SMILES: NC1=NC=NC2=C1N=CN2[C@H]3[C@H]4[C@H](OC(C)(C)O4)[C@@H](CO)O3
Biological Activity: 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes[1][2].
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2',3'-O-Isopropylideneadenosine | 99.97% | 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes. | ||||||||||||||||||||
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2',3'-O-Isopropylideneadenosine-13C5 | 2',3'-O-Isopropylideneadenosine-13C5 is the 13C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes. | |||||||||||||||||||||
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References
- [1]. Xinyi Xing, et al. A novel aggregation induced emission (AIE) fluorescence probe by combining tetraphenylethylene and 2′,3′-O-isopropylideneadenosine for localizing Golgi apparatus. Sensors and Actuators B: Chemical. Volume 329, 15 February 2021, 129245.
- [2]. S. Sprang, et al. The crystal structure and conformation of 2',3'-O-isopropylideneadenosine: the co-existence of a planar and a puckered ribofuranose ring. Acta Cryst. (1978). B34, 2803-2810.
