452-06-2
452-06-2
Chemical Structure
2-Aminopurine
- CAS No.: 452-06-2
- Formula:C5H5N5
- Molecular Weight:135.13
IUPAC Name: 7H-purin-2-amine
InChIKey: MWBWWFOAEOYUST-UHFFFAOYSA-N
SMILES: NC1=NC=C2NC=NC2=N1
Biological Activity: 2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Aminopurine | 99.54% | 2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics. | ||||||||||||||||||||
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6-Thioguanine | 99.54% | 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | ||||||||||||||||||||
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Adenine hydrochloride (Standard) | ≥98% | Adenine (hydrochloride) (Standard) is the analytical standard of Adenine (hydrochloride). This product is intended for research and analytical applications. Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Adenine (Standard) | 99.91% | Adenine (Standard) is the analytical standard of Adenine. This product is intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Adenine-13C | 99.06% | Adenine-13C is the 13C labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | ||||||||||||||||||||
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Zarzissine | Zarzissine is a cytotoxic guanidine alkaloid that can be isolated from the Mediterranean sponge Anchinoe paupertas. Zarzissine shows antimicrobial and anticancer activities. | |||||||||||||||||||||
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2-Aminopurine dihydrochloride | 2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence. | |||||||||||||||||||||
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7H-Purine-2,6-diamine | 99.99% | 7H-Purine-2,6-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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6-Thioguanine-13C2,15N | 6-Thioguanine-13C2,15N (Thioguanine-13C2,15N) is the 13C and 15N labeled 6-Thioguanine (HY-13765). 6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | |||||||||||||||||||||
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Adenine-15N5 hydrochloride | Adenine-15N5 (6-Aminopurine-15N5) hydrochloride is the 15N-labeled Adenine hydrochloride (HY-B0152A). Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. | |||||||||||||||||||||
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2-Amino-6-chloropurine | 99.79% | 6-Chloroguanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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References
- [1]. J M Jean, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):37-41. [Content Brief]
- [2]. Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.). Nat Prod Res. 2015;29(23):2219-22. [Content Brief]
