24598-73-0
Chemical Structure
Orotic acid potassium
Synonym(s): 6-Carboxyuracil potassium; Vitamin B13 potassium
- CAS No.: 24598-73-0
- Formula:C5H3KN2O4
- Molecular Weight:194.19
IUPAC Name: potassium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
InChIKey: DHBUISJCVRMTAZ-UHFFFAOYSA-M
SMILES: O=C(C(NC1=O)=CC(N1)=O)O[K]
Biological Activity: Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Orotic acid potassium | 99.51% | Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats. | ||||||||||||||||||||
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- [1]. Löffler M, et, al. Orotate (orotic acid): An essential and versatile molecule. Nucleosides Nucleotides Nucleic Acids. [Content Brief]
- [2]. Staretz-Chacham O, et, al. The role of orotic acid measurement in routine newborn screening for urea cycle disorders. J Inherit Metab Dis. 2020 Nov 15. [Content Brief]
- [3]. Durschlag RP, et, al. Orotic acid-induced metabolic changes in the rat. J Nutr. 1980 Apr;110(4):816-21. [Content Brief]
- [4]. Kochkin, et al. "Orotic acid and its derivatives. Preparation, properties, and uses." Pharmaceutical Chemistry Journal 11.8 (1977): 1155-1160.
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