5-Fluoroorotic acid (Standard)
5-Fluoroorotic acid is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid exhibits antimalarial activity.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 703-95-7
- Formula: C5H3FN2O4
- Molecular Weight:174.09
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 703-95-7
-
Molecular Weight 174.09
-
Formula C5H3FN2O4
-
SMILES
O=C(C(NC1=O)=C(F)C(N1)=O)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Boeke JD, et, al. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 1987; 154: 164-75. [Content Brief]
[2]. Nikolova K, et, al. Studies on the antimycotic activity of 5-fluoroorotic acid. Methods Find Exp Clin Pharmacol. 1987 Feb; 9(2): 85-9. [Content Brief]
[3]. Santoso D, et al., Fluoroorotic acid-selected Nicotiana plumbaginifolia cell lines with a stable thymine starvation phenotype have lost the thymine-regulated transcriptional program. Plant Physiol. 2000 Aug;123(4):1517-24. [Content Brief]
[4]. Rathod PK, et al., Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro. Antimicrob Agents Chemother. 1989 Jul;33(7):1090-4. [Content Brief]
[5]. Gómez ZM, et al., Antimalarial activity of a combination of 5-fluoroorotate and uridine in mice. Antimicrob Agents Chemother. 1990 Jul;34(7):1371-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Fluoroorotic acid (Standard) Related Classifications
HY-W016819R Related Classifications
Powered by Bioz