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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
155 Results for "
bile acids
" in MedChemExpress (MCE) Product Catalog:
Products (155)
155 Results for "bile acids" in MCE Product Catalog:
30
30 Publications Verification
Synonyms: Ursodeoxycholate; Ursodiol; UDCA
30
30 Publications Verification
Synonyms: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium
28
28 Cited Publications
Synonyms: Cholanoic acid; Desoxycholic acid
28
21
Category:
Human Gut Microbiota Metabolites Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
12
Target:
12
Target:
9
9 Cited Publications
Cat. No.: HY-104081
CAS No.: 11041-12-6
Synonyms: Cholestyramine resin; Colestyramine
Research Areas:
Cholestyramine (Cholestyramine resin) is an orally active bile acid sequestrant. Cholestyramine upregulates the expression of intestinal Apical sodium-dependent bile acid transporter and hepatic Cholesterol 7α-hydroxylase. Cholestyramine induces the expression of intestinal and hepatic cholesterol synthesis genes as well as hepatic lipogenesis genes, and promotes bile acid- and neutral sterol-mediated reverse cholesterol transport. Cholestyramine reduces intestinal cholesterol absorption and induces cholesterol efflux. Cholestyramine is applicable to research related to coronary artery disease, atherosclerotic cardiovascular disease and atherosclerosis .
8
8 Cited Publications
Cat. No.: HY-W018512
CAS No.: 4651-67-6
Synonyms: 3α-Hydroxy-7-oxo-5β-cholanic acid
Target:
7
Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice .
5
5 Cited Publications
Synonyms: T-βMCA sodium
Tauro-β-muricholic Acid sodium (T-βMCA sodium), a endogenous metabolite, is a competitive and reversible farnesoid X receptor (FXR) antagonist, with an IC50 of 40 μM .
5
4
4 Cited Publications
Cat. No.: HY-B1899A
CAS No.: 110026-03-4
Synonyms: Taurodeoxycholate sodium hydrate
3
3 Cited Publications
Synonyms: Lithocholylglycine sodium
Target:
Research Areas:
Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .
3
3 Cited Publications
Synonyms: Lithocholylglycine
Category:
Human Gut Microbiota Metabolites Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids
Target:
2
Target:
2
2 Cited Publications
2
Research Areas:
Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes .
1
1 Cited Publications
Synonyms: 3β-Hydroxy-5β-cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid
Category:
Human Gut Microbiota Metabolites Endogenous metabolite Disease Research Fields Endocrinology Steroids
Target:
1
1 Cited Publications
Cat. No.: HY-N9457
CAS No.: 60696-62-0
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
