4651-67-6
Chemical Structure
7-Ketolithocholic acid
Synonym(s): 3α-Hydroxy-7-oxo-5β-cholanic acid
- CAS No.: 4651-67-6
- Formula:C24H38O4
- Molecular Weight:390.56
IUPAC Name: (R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: DXOCDBGWDZAYRQ-AURDAFMXSA-N
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Biological Activity: 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion[1][2].
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7-Ketolithocholic acid | 99.93% | 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion. | ||||||||||||||||||||
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7-Ketolithocholic acid (Standard) | 99.87% | 7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion. | ||||||||||||||||||||
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- [1]. Choucair I, et al. Quantification of bile acids: a mass spectrometry platform for studying gut microbe connectionto metabolic diseases. J Lipid Res. 2020 Feb;61(2):159-177. [Content Brief]
- [2]. Salen G, et al. Effect of 7-ketolithocholic acid on bile acid metabolism in humans. Gastroenterology. 1982 Aug;83(2):341-7. [Content Brief]