1 Result for "

bronchioalveolar stem cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "bronchioalveolar stem cells" in MCE Product Catalog:

Cat. No.: HY-106381A
Purity:  ≥98.0%
Target:  

PKC TrxR NF-κB

Research Areas:  

Inflammation/Immunology Cancer

Aurothiomalate tetramer sodium is the tetrameric form of Aurothiomalate sodium (HY-106381). Aurothiomalate sodium acts as an inhibitor of PKCI and TrxR1. Aurothiomalate sodium disrupts the PKCI-Par6-Rac1 signaling pathway, and also inhibits TrxR1 activity, TNFα-induced NF-κB activation, and the expression of pro-inflammatory genes. Aurothiomalate sodium blocks Kras-mediated BASC expansion and lung tumor growth, inhibits anchorage-independent growth and tumorigenicity of lung cancer cells, and suppresses neutrophil chemotaxis, phagocytosis, and leukocyte extravasation. Aurothiomalate sodium can be used in research related to rheumatoid arthritis and non-small cell lung cancer .
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