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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
cardiac autonomic function
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "cardiac autonomic function" in MCE Product Catalog:
Cat. No.: HY-12502C
CAS No.: 128194-13-8
Synonyms: (R)-NZ-105; (-)-Efonidipine
Target:
Research Areas:
(R)-Efonidipine ((R)-NZ-105) is an orally active, selective T-type Ca 2+ channel blocker. (R)-Efonidipine does not inhibit high-voltage-activated Ca 2+ channels, voltage-dependent Na + channels, or Ca 2+-activated K + channels. (R)-Efonidipine modulates cardiac autonomic function by increasing parasympathetic activity and decreasing sympathetic activity. (R)-Efonidipine significantly improves survival in a mouse model of dilated cardiomyopathy. (R)-Efonidipine can be used in research on ischemic encephalopathy, heart failure, and hypertension .
Cat. No.: HY-106698
CAS No.: 57475-17-9
Target:
Research Areas:
Brovincamine is an orally active slow Ca 2+ channel blocker and vasodilator. Brovincamine reduces Ca 2+ influx across the plasma membrane by blocking Ca 2+ channels. Brovincamine inhibits catecholamine secretion, cholinergic function, autonomic parasympathetic nervous system activity, cerebrovascular resistance, and nerve stimulation-induced convulsive responses. Brovincamine induces cerebrovascular, coronary, and intracranial vasodilation, improves cerebral cortical microcirculation, enhances cerebral metabolic activity, and increases capillary clearance efficiency. Brovincamine can be used in research related to cerebral ischemic diseases, cardiac ischemic diseases, and normal-tension glaucoma .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
