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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
clathrin-coated vesicles
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "clathrin-coated vesicles" in MCE Product Catalog:
Cat. No.: HY-D2817
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FITC-PLL is a fluorescently labeled polycationic polypeptide probe composed of polylysine (PLL) and FITC (HY-66019), with a typical Ex/Em of 495/520 nm. The fluorescence intensity and lifetime of FITC-PLL are sensitive to pH and FITC density. FITC-PLL can be used for quantifying hapten receptor binding and endocytosis kinetics in macrophages, as a patternable substrate for neuron guidance, for negatively charged phospholipid membrane binding and transmembrane transport, and for live-cell imaging of starch nanoparticle conjugates and lysosome labeling .
Cat. No.: HY-179558
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MS1-96 is an orally active PD-L1 (programmed death-ligand 1) molecular glue degrader. MS1-96 effectively reduced PD-L1 protein levels across multiple colorectal cancer (CRC) cell lines. MS1-96 directly binds to PD-L1 (KD = 2.58 μM) and enhances the interaction between HIP1R and PD-L1, thereby altering the intracellular trafficking of PD-L1 within clathrin-coated vesicles. MS1-96 induces abnormal N-glycosylation of PD-L1, destabilizing the protein and hastening its lysosome-mediated degradation. MS1-96 can be used for the study of colorectal cancer .
Cat. No.: HY-D2993
CAS No.: 1418275-35-0
Synonyms: BG-TMR
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Research Areas:
SNAP-TMR (BG-TMR) is a cell-permeable fluorescent dye used for visualizing SNAP fusion proteins and performing single-molecule imaging for motor movement analysis. SNAP-TMR covalently binds to the active site of the SNAP tag domain on fusion proteins, thereby reporting the presence, localization, or movement of the protein. The excitation wavelength of SNAP-TMR is 561 nm, and the maximum labeling efficiency reaches 80% .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
